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Palmitic acid follows a different metabolic pathway than oleic acid in human skeletal muscle cells; lower lipolysis rate despite an increased level of adipose triglyceride lipase.
Bakke SS, Moro C, Nikolić N, Hessvik NP, Badin PM, Lauvhaug L, Fredriksson K, Hesselink MK, Boekschoten MV, Kersten S, Gaster M, Thoresen GH, Rustan AC. Bakke SS, et al. Among authors: nikolic n. Biochim Biophys Acta. 2012 Oct;1821(10):1323-33. doi: 10.1016/j.bbalip.2012.07.001. Epub 2012 Jul 13. Biochim Biophys Acta. 2012. PMID: 22796147
Myotubes from severely obese type 2 diabetic subjects accumulate less lipids and show higher lipolytic rate than myotubes from severely obese non-diabetic subjects.
Bakke SS, Feng YZ, Nikolić N, Kase ET, Moro C, Stensrud C, Damlien L, Ludahl MO, Sandbu R, Solheim BM, Rustan AC, Hjelmesæth J, Thoresen GH, Aas V. Bakke SS, et al. Among authors: nikolic n. PLoS One. 2015 Mar 19;10(3):e0119556. doi: 10.1371/journal.pone.0119556. eCollection 2015. PLoS One. 2015. PMID: 25790476 Free PMC article.
322 results