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Genome-Wide Association Study for Alcohol-Related Cirrhosis Identifies Risk Loci in MARC1 and HNRNPUL1.
Innes H, Buch S, Hutchinson S, Guha IN, Morling JR, Barnes E, Irving W, Forrest E, Pedergnana V, Goldberg D, Aspinall E, Barclay S, Hayes PC, Dillon J, Nischalke HD, Lutz P, Spengler U, Fischer J, Berg T, Brosch M, Eyer F, Datz C, Mueller S, Peccerella T, Deltenre P, Marot A, Soyka M, McQuillin A, Morgan MY, Hampe J, Stickel F. Innes H, et al. Among authors: nischalke hd. Gastroenterology. 2020 Oct;159(4):1276-1289.e7. doi: 10.1053/j.gastro.2020.06.014. Epub 2020 Jun 16. Gastroenterology. 2020. PMID: 32561361
The GNB3 C825T polymorphism affects response to HCV therapy with pegylated interferon in HCV/HIV co-infected but not in HCV mono-infected patients.
Ahlenstiel G, Nischalke HD, Bueren K, Berg T, Vogel M, Biermer M, Grünhage F, Sauerbruch T, Rockstroh J, Spengler U, Nattermann J. Ahlenstiel G, et al. Among authors: nischalke hd. J Hepatol. 2007 Sep;47(3):348-55. doi: 10.1016/j.jhep.2007.04.008. Epub 2007 May 24. J Hepatol. 2007. PMID: 17559964 Clinical Trial.
The HLA-E(R)/HLA-E(R) genotype affects the natural course of hepatitis C virus (HCV) infection and is associated with HLA-E-restricted recognition of an HCV-derived peptide by interferon-gamma-secreting human CD8(+) T cells.
Schulte D, Vogel M, Langhans B, Krämer B, Körner C, Nischalke HD, Steinberg V, Michalk M, Berg T, Rockstroh JK, Sauerbruch T, Spengler U, Nattermann J. Schulte D, et al. Among authors: nischalke hd. J Infect Dis. 2009 Nov 1;200(9):1397-401. doi: 10.1086/605889. J Infect Dis. 2009. PMID: 19780673
The toll-like receptor 2 (TLR2) -196 to -174 del/ins polymorphism affects viral loads and susceptibility to hepatocellular carcinoma in chronic hepatitis C.
Nischalke HD, Coenen M, Berger C, Aldenhoff K, Müller T, Berg T, Krämer B, Körner C, Odenthal M, Schulze F, Grünhage F, Nattermann J, Sauerbruch T, Spengler U. Nischalke HD, et al. Int J Cancer. 2012 Mar 15;130(6):1470-5. doi: 10.1002/ijc.26143. Epub 2011 Jun 18. Int J Cancer. 2012. PMID: 21500195 Free article.
The predictive value of IL28B gene polymorphism for spontaneous clearance in a single source outbreak cohort is limited in patients carrying the CCR5Δ32 mutation.
Nattermann J, Timm J, Nischalke HD, Olbrich A, Michalk M, Tillmann HL, Berg T, Wedemeyer H, Tenckhoff H, Wiese M, Kullig U, Göbel U, Capka E, Schiefke I, Güthof W, Grüngreiff K, König I, Roggendorf M, Sauerbruch T, Spengler U; East German HCV Study Group. Nattermann J, et al. Among authors: nischalke hd. J Hepatol. 2011 Dec;55(6):1201-6. doi: 10.1016/j.jhep.2011.03.011. Epub 2011 Apr 13. J Hepatol. 2011. PMID: 21703201
The PNPLA3 rs738409 148M/M genotype is a risk factor for liver cancer in alcoholic cirrhosis but shows no or weak association in hepatitis C cirrhosis.
Nischalke HD, Berger C, Luda C, Berg T, Müller T, Grünhage F, Lammert F, Coenen M, Krämer B, Körner C, Vidovic N, Oldenburg J, Nattermann J, Sauerbruch T, Spengler U. Nischalke HD, et al. PLoS One. 2011;6(11):e27087. doi: 10.1371/journal.pone.0027087. Epub 2011 Nov 7. PLoS One. 2011. PMID: 22087248 Free PMC article.
96 results