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Risk Locus Identification Ties Alcohol Withdrawal Symptoms to SORCS2.
Smith AH, Ovesen PL, Skeldal S, Yeo S, Jensen KP, Olsen D, Diazgranados N, Zhao H, Farrer LA, Goldman D, Glerup S, Kranzler HR, Nykjaer A, Gelernter J. Smith AH, et al. Among authors: nykjaer a. Alcohol Clin Exp Res. 2018 Dec;42(12):2337-2348. doi: 10.1111/acer.13890. Epub 2018 Oct 25. Alcohol Clin Exp Res. 2018. PMID: 30252935 Free PMC article.
SorLA regulates the activity of lipoprotein lipase by intracellular trafficking.
Klinger SC, Glerup S, Raarup MK, Mari MC, Nyegaard M, Koster G, Prabakaran T, Nilsson SK, Kjaergaard MM, Bakke O, Nykjær A, Olivecrona G, Petersen CM, Nielsen MS. Klinger SC, et al. Among authors: nykjaer a. J Cell Sci. 2011 Apr 1;124(Pt 7):1095-105. doi: 10.1242/jcs.072538. Epub 2011 Mar 8. J Cell Sci. 2011. PMID: 21385844 Free article.
Mapping of the interaction site between sortilin and the p75 neurotrophin receptor reveals a regulatory role for the sortilin intracellular domain in p75 neurotrophin receptor shedding and apoptosis.
Skeldal S, Sykes AM, Glerup S, Matusica D, Palstra N, Autio H, Boskovic Z, Madsen P, Castrén E, Nykjaer A, Coulson EJ. Skeldal S, et al. Among authors: nykjaer a. J Biol Chem. 2012 Dec 21;287(52):43798-809. doi: 10.1074/jbc.M112.374710. Epub 2012 Oct 26. J Biol Chem. 2012. PMID: 23105113 Free PMC article.
SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET.
Glerup S, Lume M, Olsen D, Nyengaard JR, Vaegter CB, Gustafsen C, Christensen EI, Kjolby M, Hay-Schmidt A, Bender D, Madsen P, Saarma M, Nykjaer A, Petersen CM. Glerup S, et al. Among authors: nykjaer a. Cell Rep. 2013 Jan 31;3(1):186-99. doi: 10.1016/j.celrep.2012.12.011. Epub 2013 Jan 17. Cell Rep. 2013. PMID: 23333276 Free article.
131 results