O'Donnell PH - Search Results

1

Identification of novel germline polymorphisms governing capecitabine sensitivity.

O'Donnell PH, Stark AL, Gamazon ER, Wheeler HE, McIlwee BE, Gorsic L, Im HK, Huang RS, Cox NJ, Dolan ME. O'Donnell PH, et al. Cancer. 2012 Aug 15;118(16):4063-73. doi: 10.1002/cncr.26737. Epub 2012 Jan 3. Cancer. 2012. PMID: 22864933 Free PMC article.

2

Cancer pharmacoethnicity: ethnic differences in susceptibility to the effects of chemotherapy.

O'Donnell PH, Dolan ME. O'Donnell PH, et al. Clin Cancer Res. 2009 Aug 1;15(15):4806-14. doi: 10.1158/1078-0432.CCR-09-0344. Epub 2009 Jul 21. Clin Cancer Res. 2009. PMID: 19622575 Free PMC article. Review.

3

Heritable and non-genetic factors as variables of pharmacologic phenotypes in lymphoblastoid cell lines.

Stark AL, Zhang W, Mi S, Duan S, O'Donnell PH, Huang RS, Dolan ME. Stark AL, et al. Pharmacogenomics J. 2010 Dec;10(6):505-12. doi: 10.1038/tpj.2010.3. Epub 2010 Feb 9. Pharmacogenomics J. 2010. PMID: 20142840 Free PMC article.

4

Population differences in platinum toxicity as a means to identify novel genetic susceptibility variants.

O'Donnell PH, Gamazon E, Zhang W, Stark AL, Kistner-Griffin EO, Stephanie Huang R, Eileen Dolan M. O'Donnell PH, et al. Pharmacogenet Genomics. 2010 May;20(5):327-37. doi: 10.1097/FPC.0b013e3283396c4e. Pharmacogenet Genomics. 2010. PMID: 20393316 Free PMC article.

5

Population differences in the rate of proliferation of international HapMap cell lines.

Stark AL, Zhang W, Zhou T, O'Donnell PH, Beiswanger CM, Huang RS, Cox NJ, Dolan ME. Stark AL, et al. Am J Hum Genet. 2010 Dec 10;87(6):829-33. doi: 10.1016/j.ajhg.2010.10.018. Epub 2010 Nov 25. Am J Hum Genet. 2010. PMID: 21109222 Free PMC article.

6

Comprehensive evaluation of the contribution of X chromosome genes to platinum sensitivity.

Gamazon ER, Im HK, O'Donnell PH, Ziliak D, Stark AL, Cox NJ, Dolan ME, Huang RS. Gamazon ER, et al. Mol Cancer Ther. 2011 Mar;10(3):472-80. doi: 10.1158/1535-7163.MCT-10-0910. Epub 2011 Jan 20. Mol Cancer Ther. 2011. PMID: 21252287 Free PMC article.

7

Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers.

Ziliak D, O'Donnell PH, Im HK, Gamazon ER, Chen P, Delaney S, Shukla S, Das S, Cox NJ, Vokes EE, Cohen EE, Dolan ME, Huang RS. Ziliak D, et al. Transl Res. 2011 May;157(5):265-72. doi: 10.1016/j.trsl.2011.01.005. Epub 2011 Feb 8. Transl Res. 2011. PMID: 21497773 Free PMC article.

8

Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients.

Huang RS, Johnatty SE, Gamazon ER, Im HK, Ziliak D, Duan S, Zhang W, Kistner EO, Chen P, Beesley J, Mi S, O'Donnell PH, Fraiman YS, Das S, Cox NJ, Lu Y, Macgregor S, Goode EL, Vierkant RA, Fridley BL, Hogdall E, Kjaer SK, Jensen A, Moysich KB, Grasela M, Odunsi K, Brown R, Paul J, Lambrechts D, Despierre E, Vergote I, Gross J, Karlan BY, Defazio A, Chenevix-Trench G; Australian Ovarian Cancer Study Group; Dolan ME. Huang RS, et al. Clin Cancer Res. 2011 Aug 15;17(16):5490-500. doi: 10.1158/1078-0432.CCR-11-0724. Epub 2011 Jun 24. Clin Cancer Res. 2011. PMID: 21705454 Free PMC article.

9

Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations.

Wheeler HE, Gamazon ER, Stark AL, O'Donnell PH, Gorsic LK, Huang RS, Cox NJ, Dolan ME. Wheeler HE, et al. Pharmacogenomics J. 2013 Feb;13(1):35-43. doi: 10.1038/tpj.2011.38. Epub 2011 Aug 16. Pharmacogenomics J. 2013. PMID: 21844884 Free PMC article.

10

The 1200 patients project: creating a new medical model system for clinical implementation of pharmacogenomics.

O'Donnell PH, Bush A, Spitz J, Danahey K, Saner D, Das S, Cox NJ, Ratain MJ. O'Donnell PH, et al. Clin Pharmacol Ther. 2012 Oct;92(4):446-9. doi: 10.1038/clpt.2012.117. Epub 2012 Aug 29. Clin Pharmacol Ther. 2012. PMID: 22929923 Free PMC article. Review.

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