O'Rahilly S - Search Results

1

Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.

Lotta LA, Wittemans LBL, Zuber V, Stewart ID, Sharp SJ, Luan J, Day FR, Li C, Bowker N, Cai L, De Lucia Rolfe E, Khaw KT, Perry JRB, O'Rahilly S, Scott RA, Savage DB, Burgess S, Wareham NJ, Langenberg C. Lotta LA, et al. JAMA. 2018 Dec 25;320(24):2553-2563. doi: 10.1001/jama.2018.19329. JAMA. 2018. PMID: 30575882 Free PMC article.

2

Sequence variants in the melatonin-related receptor gene (GPR50) associate with circulating triglyceride and HDL levels.

Bhattacharyya S, Luan J, Challis B, Keogh J, Montague C, Brennand J, Morten J, Lowenbeim S, Jenkins S, Farooqi IS, Wareham NJ, O'Rahilly S. Bhattacharyya S, et al. J Lipid Res. 2006 Apr;47(4):761-6. doi: 10.1194/jlr.M500338-JLR200. Epub 2006 Jan 25. J Lipid Res. 2006. PMID: 16436372 Free article.

3

Genetic variants and common diseases--better late than never.

O'Rahilly S, Wareham NJ. O'Rahilly S, et al. N Engl J Med. 2006 Jul 20;355(3):306-8. doi: 10.1056/NEJMe068140. N Engl J Med. 2006. PMID: 16855272 No abstract available.

4

Non-DNA binding, dominant-negative, human PPARgamma mutations cause lipodystrophic insulin resistance.

Agostini M, Schoenmakers E, Mitchell C, Szatmari I, Savage D, Smith A, Rajanayagam O, Semple R, Luan J, Bath L, Zalin A, Labib M, Kumar S, Simpson H, Blom D, Marais D, Schwabe J, Barroso I, Trembath R, Wareham N, Nagy L, Gurnell M, O'Rahilly S, Chatterjee K. Agostini M, et al. Cell Metab. 2006 Oct;4(4):303-11. doi: 10.1016/j.cmet.2006.09.003. Cell Metab. 2006. PMID: 17011503 Free PMC article.

5

Comment on "A common genetic variant is associated with adult and childhood obesity".

Loos RJ, Barroso I, O'rahilly S, Wareham NJ. Loos RJ, et al. Science. 2007 Jan 12;315(5809):187; author reply 187. doi: 10.1126/science.1130012. Science. 2007. PMID: 17218509 Free PMC article.

6

Paradoxical elevation of high-molecular weight adiponectin in acquired extreme insulin resistance due to insulin receptor antibodies.

Semple RK, Halberg NH, Burling K, Soos MA, Schraw T, Luan J, Cochran EK, Dunger DB, Wareham NJ, Scherer PE, Gorden P, O'Rahilly S. Semple RK, et al. Diabetes. 2007 Jun;56(6):1712-7. doi: 10.2337/db06-1665. Epub 2007 Feb 26. Diabetes. 2007. PMID: 17325257 Free PMC article.

7

Analysis of genetic variation in Akt2/PKB-beta in severe insulin resistance, lipodystrophy, type 2 diabetes, and related metabolic phenotypes.

Tan K, Kimber WA, Luan J, Soos MA, Semple RK, Wareham NJ, O'Rahilly S, Barroso I. Tan K, et al. Diabetes. 2007 Mar;56(3):714-9. doi: 10.2337/db06-0921. Diabetes. 2007. PMID: 17327441 Free PMC article.

8

Lamin A/C polymorphisms, type 2 diabetes, and the metabolic syndrome: case-control and quantitative trait studies.

Mesa JL, Loos RJ, Franks PW, Ong KK, Luan J, O'Rahilly S, Wareham NJ, Barroso I. Mesa JL, et al. Diabetes. 2007 Mar;56(3):884-9. doi: 10.2337/db06-1055. Diabetes. 2007. PMID: 17327461 Free PMC article.

9

TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population.

Loos RJ, Franks PW, Francis RW, Barroso I, Gribble FM, Savage DB, Ong KK, O'Rahilly S, Wareham NJ. Loos RJ, et al. Diabetes. 2007 Jul;56(7):1943-7. doi: 10.2337/db07-0055. Epub 2007 Apr 6. Diabetes. 2007. PMID: 17416797 Free PMC article.

10

A clinical approach to severe insulin resistance.

Savage DB, Semple RK, Chatterjee VKK, Wales JKH, Ross RJM, O'Rahilly S. Savage DB, et al. Endocr Dev. 2007;11:122-132. doi: 10.1159/000111067. Endocr Dev. 2007. PMID: 17986832 Review.

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