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Mnk2 alternative splicing modulates the p38-MAPK pathway and impacts Ras-induced transformation.
Maimon A, Mogilevsky M, Shilo A, Golan-Gerstl R, Obiedat A, Ben-Hur V, Lebenthal-Loinger I, Stein I, Reich R, Beenstock J, Zehorai E, Andersen CL, Thorsen K, Ørntoft TF, Davis RJ, Davidson B, Mu D, Karni R. Maimon A, et al. Among authors: obiedat a. Cell Rep. 2014 Apr 24;7(2):501-513. doi: 10.1016/j.celrep.2014.03.041. Epub 2014 Apr 13. Cell Rep. 2014. PMID: 24726367 Free article.
The integrated stress response promotes B7H6 expression.
Obiedat A, Charpak-Amikam Y, Tai-Schmiedel J, Seidel E, Mahameed M, Avril T, Stern-Ginossar N, Springuel L, Bolsée J, Gilham DE, Dipta P, Shmuel M, Chevet E, Mandelboim O, Tirosh B. Obiedat A, et al. J Mol Med (Berl). 2020 Jan;98(1):135-148. doi: 10.1007/s00109-019-01859-w. Epub 2019 Dec 14. J Mol Med (Berl). 2020. PMID: 31838577 Free PMC article.
Transcription of the NKG2D ligand MICA is suppressed by the IRE1/XBP1 pathway of the unfolded protein response through the regulation of E2F1.
Obiedat A, Seidel E, Mahameed M, Berhani O, Tsukerman P, Voutetakis K, Chatziioannou A, McMahon M, Avril T, Chevet E, Mandelboim O, Tirosh B. Obiedat A, et al. FASEB J. 2019 Mar;33(3):3481-3495. doi: 10.1096/fj.201801350RR. Epub 2018 Nov 19. FASEB J. 2019. PMID: 30452881
Deletion of IRE1 or XBP1 was sufficient to promote mRNA and surface levels of MICA. Accordingly, NKG2D played a greater role in the killing of IRE1/XBP1 knockout target cells. ...Because of the importance of E2F1 and MICA in cancer progression and recognition, these observ …
Deletion of IRE1 or XBP1 was sufficient to promote mRNA and surface levels of MICA. Accordingly, NKG2D played a greater role in the k …
IRE1 endoribonuclease signaling promotes myeloid cell infiltration in glioblastoma.
Obacz J, Archambeau J, Lafont E, Nivet M, Martin S, Aubry M, Voutetakis K, Pineau R, Boniface R, Sicari D, Pelizzari-Raymundo D, Ghukasyan G, McGrath E, Vlachavas EI, Le Gallo M, Le Reste PJ, Barroso K, Fainsod-Levi T, Obiedat A, Granot Z, Tirosh B, Samal J, Pandit A, Négroni L, Soriano N, Monnier A, Mosser J, Chatziioannou A, Quillien V, Chevet E, Avril T. Obacz J, et al. Among authors: obiedat a. Neuro Oncol. 2023 Dec 28:noad256. doi: 10.1093/neuonc/noad256. Online ahead of print. Neuro Oncol. 2023. PMID: 38153426
Validation of CHA2DS2 VASc Score Predictability of Stroke and Systemic Embolization in a Middle Eastern Population with AF: The Jordan Atrial Fibrillation (JoFib) Study.
Ibdah R, Obeidat O, Khader Y, Al-Nusair J, Abusurrah O, Obeidat A, Obeidat A, Rawashdeh S, Alrabadi N, Obiedat AF, Alnadi NN, Hammoudeh A. Ibdah R, et al. Among authors: obiedat af. Vasc Health Risk Manag. 2023 Apr 24;19:255-264. doi: 10.2147/VHRM.S404575. eCollection 2023. Vasc Health Risk Manag. 2023. PMID: 37125391 Free PMC article.
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