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Pharmacokinetic and pharmacodynamic properties of the glucokinase activator MK-0941 in rodent models of type 2 diabetes and healthy dogs.
Eiki J, Nagata Y, Futamura M, Sasaki-Yamamoto K, Iino T, Nishimura T, Chiba M, Ohyama S, Yoshida-Yoshimioto R, Fujii K, Hosaka H, Goto-Shimazaki H, Kadotani A, Ohe T, Lin S, Langdon RB, Berger JP. Eiki J, et al. Among authors: ohe t. Mol Pharmacol. 2011 Dec;80(6):1156-65. doi: 10.1124/mol.111.074401. Epub 2011 Sep 21. Mol Pharmacol. 2011. PMID: 21937665
5,5-Dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione, a potent inhibitor for mammalian elongase of long-chain fatty acids family 6: examination of its potential utility as a pharmacological tool.
Shimamura K, Kitazawa H, Miyamoto Y, Kanesaka M, Nagumo A, Yoshimoto R, Aragane K, Morita N, Ohe T, Takahashi T, Nagase T, Sato N, Tokita S. Shimamura K, et al. Among authors: ohe t. J Pharmacol Exp Ther. 2009 Jul;330(1):249-56. doi: 10.1124/jpet.109.150854. Epub 2009 Apr 9. J Pharmacol Exp Ther. 2009. PMID: 19359527
Identification of positron emission tomography ligands for NPY Y5 receptors in the brain.
Takahashi H, Haga Y, Shibata T, Nonoshita K, Sakamoto T, Moriya M, Ohe T, Chiba M, Mitobe Y, Kitazawa H, Iwaasa H, Ishihara A, Ishii Y, Kanatani A, Fukami T. Takahashi H, et al. Among authors: ohe t. Bioorg Med Chem Lett. 2009 Sep 15;19(18):5436-9. doi: 10.1016/j.bmcl.2009.07.103. Epub 2009 Jul 25. Bioorg Med Chem Lett. 2009. PMID: 19679469
519 results