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Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease.
Crawford AA, Bankier S, Altmaier E, Barnes CLK, Clark DW, Ermel R, Friedrich N, van der Harst P, Joshi PK, Karhunen V, Lahti J, Mahajan A, Mangino M, Nethander M, Neumann A, Pietzner M, Sukhavasi K, Wang CA, Bakker SJL, Bjorkegren JLM, Campbell H, Eriksson J, Gieger C, Hayward C, Jarvelin MR, McLachlan S, Morris AP, Ohlsson C, Pennell CE, Price J, Rudan I, Ruusalepp A, Spector T, Tiemeier H, Völzke H, Wilson JF, Michoel T, Timpson NJ, Smith GD, Walker BR; CORtisol NETwork (CORNET) consortium. Crawford AA, et al. Among authors: ohlsson c. J Hum Genet. 2021 Jun;66(6):625-636. doi: 10.1038/s10038-020-00895-6. Epub 2021 Jan 20. J Hum Genet. 2021. PMID: 33469137 Free PMC article.
The COMT val158met polymorphism is associated with peak BMD in men.
Lorentzon M, Eriksson AL, Mellström D, Ohlsson C. Lorentzon M, et al. Among authors: ohlsson c. J Bone Miner Res. 2004 Dec;19(12):2005-11. doi: 10.1359/JBMR.040909. Epub 2004 Sep 20. J Bone Miner Res. 2004. PMID: 15537444 Free article.
SHBG gene promoter polymorphisms in men are associated with serum sex hormone-binding globulin, androgen and androgen metabolite levels, and hip bone mineral density.
Eriksson AL, Lorentzon M, Mellström D, Vandenput L, Swanson C, Andersson N, Hammond GL, Jakobsson J, Rane A, Orwoll ES, Ljunggren O, Johnell O, Labrie F, Windahl SH, Ohlsson C. Eriksson AL, et al. Among authors: ohlsson c. J Clin Endocrinol Metab. 2006 Dec;91(12):5029-37. doi: 10.1210/jc.2006-0679. Epub 2006 Aug 22. J Clin Endocrinol Metab. 2006. PMID: 16926255
746 results