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Oral biopharmaceutics tools - time for a new initiative - an introduction to the IMI project OrBiTo.
Lennernäs H, Aarons L, Augustijns P, Beato S, Bolger M, Box K, Brewster M, Butler J, Dressman J, Holm R, Julia Frank K, Kendall R, Langguth P, Sydor J, Lindahl A, McAllister M, Muenster U, Müllertz A, Ojala K, Pepin X, Reppas C, Rostami-Hodjegan A, Verwei M, Weitschies W, Wilson C, Karlsson C, Abrahamsson B. Lennernäs H, et al. Among authors: ojala k. Eur J Pharm Sci. 2014 Jun 16;57:292-9. doi: 10.1016/j.ejps.2013.10.012. Epub 2013 Nov 1. Eur J Pharm Sci. 2014. PMID: 24189462 Review.
A survey on IVIVC/IVIVR development in the pharmaceutical industry - Past experience and current perspectives.
Nguyen MA, Flanagan T, Brewster M, Kesisoglou F, Beato S, Biewenga J, Crison J, Holm R, Li R, Mannaert E, McAllister M, Mueller-Zsigmondy M, Muenster U, Ojala K, Page S, Parr A, Rossenu S, Timmins P, Van Peer A, Vermeulen A, Langguth P. Nguyen MA, et al. Among authors: ojala k. Eur J Pharm Sci. 2017 May 1;102:1-13. doi: 10.1016/j.ejps.2017.02.029. Epub 2017 Feb 21. Eur J Pharm Sci. 2017. PMID: 28235611 Review.
Validation of Dissolution Testing with Biorelevant Media: An OrBiTo Study.
Mann J, Dressman J, Rosenblatt K, Ashworth L, Muenster U, Frank K, Hutchins P, Williams J, Klumpp L, Wielockx K, Berben P, Augustijns P, Holm R, Hofmann M, Patel S, Beato S, Ojala K, Tomaszewska I, Bruel JL, Butler J. Mann J, et al. Among authors: ojala k. Mol Pharm. 2017 Dec 4;14(12):4192-4201. doi: 10.1021/acs.molpharmaceut.7b00198. Epub 2017 Aug 23. Mol Pharm. 2017. PMID: 28737403
Biorelevant dissolution testing of a weak base: Interlaboratory reproducibility and investigation of parameters controlling in vitro precipitation.
Berben P, Ashworth L, Beato S, Bevernage J, Bruel JL, Butler J, Dressman J, Schäfer K, Hutchins P, Klumpp L, Mann J, Nicolai J, Ojala K, Patel S, Powell S, Rosenblatt K, Tomaszewska I, Williams J, Augustijns P. Berben P, et al. Among authors: ojala k. Eur J Pharm Biopharm. 2019 Jul;140:141-148. doi: 10.1016/j.ejpb.2019.04.017. Epub 2019 Apr 30. Eur J Pharm Biopharm. 2019. PMID: 31051249
Interlaboratory Validation of Small-Scale Solubility and Dissolution Measurements of Poorly Water-Soluble Drugs.
Andersson SBE, Alvebratt C, Bevernage J, Bonneau D, da Costa Mathews C, Dattani R, Edueng K, He Y, Holm R, Madsen C, Müller T, Muenster U, Müllertz A, Ojala K, Rades T, Sieger P, Bergström CAS. Andersson SBE, et al. Among authors: ojala k. J Pharm Sci. 2016 Sep;105(9):2864-2872. doi: 10.1016/j.xphs.2016.03.010. Epub 2016 Apr 23. J Pharm Sci. 2016. PMID: 27112289
Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method.
Plum J, Madsen CM, Teleki A, Bevernage J, da Costa Mathews C, Karlsson EM, Carlert S, Holm R, Müller T, Matthews W, Sayers A, Ojala K, Tsinsman K, Lingamaneni R, Bergström CA, Rades T, Müllertz A. Plum J, et al. Among authors: ojala k. Mol Pharm. 2017 Dec 4;14(12):4161-4169. doi: 10.1021/acs.molpharmaceut.7b00419. Epub 2017 Nov 7. Mol Pharm. 2017. PMID: 29043811
164 results