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Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B.
Olsen OE, Wader KF, Hella H, Mylin AK, Turesson I, Nesthus I, Waage A, Sundan A, Holien T. Olsen OE, et al. Cell Commun Signal. 2015 Jun 6;13:27. doi: 10.1186/s12964-015-0104-z. Cell Commun Signal. 2015. PMID: 26047946 Free PMC article.
Growth differentiation factor 15 (GDF15) promotes osteoclast differentiation and inhibits osteoblast differentiation and high serum GDF15 levels are associated with multiple myeloma bone disease.
Westhrin M, Moen SH, Holien T, Mylin AK, Heickendorff L, Olsen OE, Sundan A, Turesson I, Gimsing P, Waage A, Standal T. Westhrin M, et al. Among authors: olsen oe. Haematologica. 2015 Dec;100(12):e511-4. doi: 10.3324/haematol.2015.124511. Epub 2015 Aug 20. Haematologica. 2015. PMID: 26294726 Free PMC article. No abstract available.
TGF-β contamination of purified recombinant GDF15.
Olsen OE, Skjærvik A, Størdal BF, Sundan A, Holien T. Olsen OE, et al. PLoS One. 2017 Nov 21;12(11):e0187349. doi: 10.1371/journal.pone.0187349. eCollection 2017. PLoS One. 2017. PMID: 29161287 Free PMC article.
BMPR2 inhibits activin and BMP signaling via wild-type ALK2.
Olsen OE, Sankar M, Elsaadi S, Hella H, Buene G, Darvekar SR, Misund K, Katagiri T, Knaus P, Holien T. Olsen OE, et al. J Cell Sci. 2018 Jun 11;131(11):jcs213512. doi: 10.1242/jcs.213512. J Cell Sci. 2018. PMID: 29739878
FKBP12 is a major regulator of ALK2 activity in multiple myeloma cells.
Quist-Løkken I, Andersson-Rusch C, Kastnes MH, Kolos JM, Jatzlau J, Hella H, Olsen OE, Sundan A, Knaus P, Hausch F, Holien T. Quist-Løkken I, et al. Among authors: olsen oe. Cell Commun Signal. 2023 Jan 30;21(1):25. doi: 10.1186/s12964-022-01033-9. Cell Commun Signal. 2023. PMID: 36717825 Free PMC article.
130 results