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The hepatotoxic fluoroquinolone trovafloxacin disturbs TNF- and LPS-induced p65 nuclear translocation in vivo and in vitro.
Giustarini G, Huppelschoten S, Barra M, Oppelt A, Wagenaar L, Weaver RJ, Bol-Schoenmakers M, Smit JJ, van de Water B, Klingmüller U, Pieters RHH. Giustarini G, et al. Among authors: oppelt a. Toxicol Appl Pharmacol. 2020 Mar 15;391:114915. doi: 10.1016/j.taap.2020.114915. Epub 2020 Feb 6. Toxicol Appl Pharmacol. 2020. PMID: 32035082
Model-based identification of TNFα-induced IKKβ-mediated and IκBα-mediated regulation of NFκB signal transduction as a tool to quantify the impact of drug-induced liver injury compounds.
Oppelt A, Kaschek D, Huppelschoten S, Sison-Young R, Zhang F, Buck-Wiese M, Herrmann F, Malkusch S, Krüger CL, Meub M, Merkt B, Zimmermann L, Schofield A, Jones RP, Malik H, Schilling M, Heilemann M, van de Water B, Goldring CE, Park BK, Timmer J, Klingmüller U. Oppelt A, et al. NPJ Syst Biol Appl. 2018 Jun 11;4:23. doi: 10.1038/s41540-018-0058-z. eCollection 2018. NPJ Syst Biol Appl. 2018. PMID: 29900006 Free PMC article.
FLASHlab@PITZ: New R&D platform with unique capabilities for electron FLASH and VHEE radiation therapy and radiation biology under preparation at PITZ.
Stephan F, Gross M, Grebinyk A, Aboulbanine Z, Amirkhanyan Z, Budach V, Ehrhardt VH, Faus-Golfe A, Frohme M, Germond JF, Good JD, Grüner F, Kaul D, Krasilnikov M, Leavitt R, Leemans W, Li X, Loisch G, Müller F, Müller G, Obier F, Oppelt A, Philipp S, Qian H, Reindl J, Riemer F, Sack M, Schmitz M, Schnautz T, Schüller A, Staufer T, Stegmann C, Tsakanova G, Vozenin MC, Weise H, Worm S, Zips D. Stephan F, et al. Among authors: oppelt a. Phys Med. 2022 Dec;104:174-187. doi: 10.1016/j.ejmp.2022.10.026. Epub 2022 Dec 1. Phys Med. 2022. PMID: 36463582
Passive Ballistic Microbunching of Nonultrarelativistic Electron Bunches Using Electromagnetic Wakefields in Dielectric-Lined Waveguides.
Lemery F, Piot P, Amatuni G, Boonpornprasert P, Chen Y, Good J, Grigoryan B, Groß M, Krasilinikov M, Lishilin O, Loisch G, Oppelt A, Philipp S, Qian H, Renier Y, Stephan F, Zagorodnov I. Lemery F, et al. Among authors: oppelt a. Phys Rev Lett. 2019 Feb 1;122(4):044801. doi: 10.1103/PhysRevLett.122.044801. Phys Rev Lett. 2019. PMID: 30768287
67 results