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Page 1
Hemophagocytic lymphohistiocytosis in leprosy.
Høyvoll LR, Fløisand Y, Orrem HL, Gunnarsson R, Landrø L, Brevig T, Gaustad P, Nordøy I. Høyvoll LR, et al. Among authors: orrem hl. Lepr Rev. 2015 Dec;86(4):403-6. Lepr Rev. 2015. PMID: 26964439
Complement ratios C3bc/C3 and sC5b-9/C5 do not increase the sensitivity of detecting acute complement activation systemically.
Thomas AM, Chaban V, Pischke SE, Orrem HL, Bosnes V, Sunde K, Seljeflot I, Lundqvist C, Nakstad ER, Andersen GØ, Schjalm C, Mollnes TE, Barratt-Due A. Thomas AM, et al. Among authors: orrem hl. Mol Immunol. 2022 Jan;141:273-279. doi: 10.1016/j.molimm.2021.11.016. Epub 2021 Dec 11. Mol Immunol. 2022. PMID: 34906905 Free article.
Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock.
Orrem HL, Nilsson PH, Pischke SE, Grindheim G, Garred P, Seljeflot I, Husebye T, Aukrust P, Yndestad A, Andersen GØ, Barratt-Due A, Mollnes TE. Orrem HL, et al. ESC Heart Fail. 2018 Jun;5(3):292-301. doi: 10.1002/ehf2.12266. Epub 2018 Feb 9. ESC Heart Fail. 2018. PMID: 29424484 Free PMC article. Clinical Trial.
IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction.
Orrem HL, Nilsson PH, Pischke SE, Kleveland O, Yndestad A, Ekholt K, Damås JK, Espevik T, Bendz B, Halvorsen B, Gregersen I, Wiseth R, Andersen GØ, Ueland T, Gullestad L, Aukrust P, Barratt-Due A, Mollnes TE. Orrem HL, et al. Front Immunol. 2018 Sep 12;9:2035. doi: 10.3389/fimmu.2018.02035. eCollection 2018. Front Immunol. 2018. PMID: 30258440 Free PMC article. Clinical Trial.
Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function.
Pischke SE, Gustavsen A, Orrem HL, Egge KH, Courivaud F, Fontenelle H, Despont A, Bongoni AK, Rieben R, Tønnessen TI, Nunn MA, Scott H, Skulstad H, Barratt-Due A, Mollnes TE. Pischke SE, et al. Among authors: orrem hl. Basic Res Cardiol. 2017 May;112(3):20. doi: 10.1007/s00395-017-0610-9. Epub 2017 Mar 3. Basic Res Cardiol. 2017. PMID: 28258298 Free PMC article.
Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis.
Hellerud BC, Orrem HL, Dybwik K, Pischke SE, Baratt-Due A, Castellheim A, Fure H, Bergseth G, Christiansen D, Nunn MA, Espevik T, Lau C, Brandtzæg P, Nielsen EW, Mollnes TE. Hellerud BC, et al. Among authors: orrem hl. J Intensive Care. 2017 Feb 27;5:21. doi: 10.1186/s40560-017-0217-0. eCollection 2017. J Intensive Care. 2017. PMID: 28261486 Free PMC article.
Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis.
Niyonzima N, Bakke SS, Gregersen I, Holm S, Sandanger Ø, Orrem HL, Sporsheim B, Ryan L, Kong XY, Dahl TB, Skjelland M, Sørensen KK, Rokstad AM, Yndestad A, Latz E, Gullestad L, Andersen GØ, Damås JK, Aukrust P, Mollnes TE, Halvorsen B, Espevik T. Niyonzima N, et al. Among authors: orrem hl. EBioMedicine. 2020 Oct;60:102985. doi: 10.1016/j.ebiom.2020.102985. Epub 2020 Sep 11. EBioMedicine. 2020. PMID: 32927275 Free PMC article.