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Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.
Daya M, Rafaels N, Brunetti TM, Chavan S, Levin AM, Shetty A, Gignoux CR, Boorgula MP, Wojcik G, Campbell M, Vergara C, Torgerson DG, Ortega VE, Doumatey A, Johnston HR, Acevedo N, Araujo MI, Avila PC, Belbin G, Bleecker E, Bustamante C, Caraballo L, Cruz A, Dunston GM, Eng C, Faruque MU, Ferguson TS, Figueiredo C, Ford JG, Gan W, Gourraud PA, Hansel NN, Hernandez RD, Herrera-Paz EF, Jiménez S, Kenny EE, Knight-Madden J, Kumar R, Lange LA, Lange EM, Lizee A, Maul P, Maul T, Mayorga A, Meyers D, Nicolae DL, O'Connor TD, Oliveira RR, Olopade CO, Olopade O, Qin ZS, Rotimi C, Vince N, Watson H, Wilks RJ, Wilson JG, Salzberg S, Ober C, Burchard EG, Williams LK, Beaty TH, Taub MA, Ruczinski I, Mathias RA, Barnes KC; CAAPA. Daya M, et al. Among authors: ortega ve. Nat Commun. 2019 Feb 20;10(1):880. doi: 10.1038/s41467-019-08469-7. Nat Commun. 2019. PMID: 30787307 Free PMC article.
A Roadmap to functional genomics.
Penn RB, Ortega VE, Bleecker ER. Penn RB, et al. Among authors: ortega ve. Physiol Genomics. 2007 Jun 19;30(1):82-8. doi: 10.1152/physiolgenomics.00010.2007. Epub 2007 Feb 27. Physiol Genomics. 2007. PMID: 17327496
Pharmacogenetics of the beta 2-adrenergic receptor gene.
Ortega VE, Hawkins GA, Peters SP, Bleecker ER. Ortega VE, et al. Immunol Allergy Clin North Am. 2007 Nov;27(4):665-84; vii. doi: 10.1016/j.iac.2007.09.007. Immunol Allergy Clin North Am. 2007. PMID: 17996583 Free PMC article. Review.
Biomarker surrogates do not accurately predict sputum eosinophil and neutrophil percentages in asthmatic subjects.
Hastie AT, Moore WC, Li H, Rector BM, Ortega VE, Pascual RM, Peters SP, Meyers DA, Bleecker ER; National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Hastie AT, et al. Among authors: ortega ve. J Allergy Clin Immunol. 2013 Jul;132(1):72-80. doi: 10.1016/j.jaci.2013.03.044. Epub 2013 May 21. J Allergy Clin Immunol. 2013. PMID: 23706399 Free PMC article.
Effect of rare variants in ADRB2 on risk of severe exacerbations and symptom control during longacting β agonist treatment in a multiethnic asthma population: a genetic study.
Ortega VE, Hawkins GA, Moore WC, Hastie AT, Ampleford EJ, Busse WW, Castro M, Chardon D, Erzurum SC, Israel E, Montealegre F, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. Ortega VE, et al. Lancet Respir Med. 2014 Mar;2(3):204-13. doi: 10.1016/S2213-2600(13)70289-3. Epub 2014 Jan 27. Lancet Respir Med. 2014. PMID: 24621682 Free PMC article.
Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry.
Kessler MD, Yerges-Armstrong L, Taub MA, Shetty AC, Maloney K, Jeng LJB, Ruczinski I, Levin AM, Williams LK, Beaty TH, Mathias RA, Barnes KC; Consortium on Asthma among African-ancestry Populations in the Americas (CAAPA); O'Connor TD. Kessler MD, et al. Nat Commun. 2016 Oct 11;7:12521. doi: 10.1038/ncomms12521. Nat Commun. 2016. PMID: 27725664 Free PMC article.
160 results