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Co-regulatory networks of human serum proteins link genetics to disease.
Emilsson V, Ilkov M, Lamb JR, Finkel N, Gudmundsson EF, Pitts R, Hoover H, Gudmundsdottir V, Horman SR, Aspelund T, Shu L, Trifonov V, Sigurdsson S, Manolescu A, Zhu J, Olafsson Ö, Jakobsdottir J, Lesley SA, To J, Zhang J, Harris TB, Launer LJ, Zhang B, Eiriksdottir G, Yang X, Orth AP, Jennings LL, Gudnason V. Emilsson V, et al. Among authors: orth ap. Science. 2018 Aug 24;361(6404):769-773. doi: 10.1126/science.aaq1327. Epub 2018 Aug 2. Science. 2018. PMID: 30072576 Free PMC article.
Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency.
Gonzalez R, Jennings LL, Knuth M, Orth AP, Klock HE, Ou W, Feuerhelm J, Hull MV, Koesema E, Wang Y, Zhang J, Wu C, Cho CY, Su AI, Batalov S, Chen H, Johnson K, Laffitte B, Nguyen DG, Snyder EY, Schultz PG, Harris JL, Lesley SA. Gonzalez R, et al. Among authors: orth ap. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3552-7. doi: 10.1073/pnas.0914019107. Epub 2010 Feb 2. Proc Natl Acad Sci U S A. 2010. PMID: 20133595 Free PMC article.
High-content screening of functional genomic libraries.
Rines DR, Tu B, Miraglia L, Welch GL, Zhang J, Hull MV, Orth AP, Chanda SK. Rines DR, et al. Among authors: orth ap. Methods Enzymol. 2006;414:530-65. doi: 10.1016/S0076-6879(06)14028-8. Methods Enzymol. 2006. PMID: 17110210
Gene set enrichment in eQTL data identifies novel annotations and pathway regulators.
Wu C, Delano DL, Mitro N, Su SV, Janes J, McClurg P, Batalov S, Welch GL, Zhang J, Orth AP, Walker JR, Glynne RJ, Cooke MP, Takahashi JS, Shimomura K, Kohsaka A, Bass J, Saez E, Wiltshire T, Su AI. Wu C, et al. Among authors: orth ap. PLoS Genet. 2008 May 9;4(5):e1000070. doi: 10.1371/journal.pgen.1000070. PLoS Genet. 2008. PMID: 18464898 Free PMC article.
58 results