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Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution.
Eirew P, Steif A, Khattra J, Ha G, Yap D, Farahani H, Gelmon K, Chia S, Mar C, Wan A, Laks E, Biele J, Shumansky K, Rosner J, McPherson A, Nielsen C, Roth AJ, Lefebvre C, Bashashati A, de Souza C, Siu C, Aniba R, Brimhall J, Oloumi A, Osako T, Bruna A, Sandoval JL, Algara T, Greenwood W, Leung K, Cheng H, Xue H, Wang Y, Lin D, Mungall AJ, Moore R, Zhao Y, Lorette J, Nguyen L, Huntsman D, Eaves CJ, Hansen C, Marra MA, Caldas C, Shah SP, Aparicio S. Eirew P, et al. Among authors: osako t. Nature. 2015 Feb 19;518(7539):422-6. doi: 10.1038/nature13952. Epub 2014 Nov 26. Nature. 2015. PMID: 25470049 Free PMC article.
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.
Xu H, Di Antonio M, McKinney S, Mathew V, Ho B, O'Neil NJ, Santos ND, Silvester J, Wei V, Garcia J, Kabeer F, Lai D, Soriano P, Banáth J, Chiu DS, Yap D, Le DD, Ye FB, Zhang A, Thu K, Soong J, Lin SC, Tsai AH, Osako T, Algara T, Saunders DN, Wong J, Xian J, Bally MB, Brenton JD, Brown GW, Shah SP, Cescon D, Mak TW, Caldas C, Stirling PC, Hieter P, Balasubramanian S, Aparicio S. Xu H, et al. Among authors: osako t. Nat Commun. 2017 Feb 17;8:14432. doi: 10.1038/ncomms14432. Nat Commun. 2017. PMID: 28211448 Free PMC article.
A prediction model for early systemic recurrence in breast cancer using a molecular diagnostic analysis of sentinel lymph nodes: A large-scale, multicenter cohort study.
Osako T, Matsuura M, Yotsumoto D, Takayama S, Kaneko K, Takahashi M, Shimazu K, Yoshidome K, Kuraoka K, Itakura M, Tani M, Ishikawa T, Ohi Y, Kinoshita T, Sato N, Tsujimoto M, Nakamura S, Tsuda H, Noguchi S, Akiyama F. Osako T, et al. Cancer. 2022 May 15;128(10):1913-1920. doi: 10.1002/cncr.34144. Epub 2022 Feb 28. Cancer. 2022. PMID: 35226357 Free PMC article. Clinical Trial.
Assessment of a cancer genomic profile test for patients with metastatic breast cancer.
Fukada I, Mori S, Hayashi N, Hosonaga M, Yamazaki M, Wang X, Kawai S, Inagaki L, Ozaki Y, Kobayashi K, Hara F, Kobayashi T, Ueki A, Osako T, Tonooka A, Takeuchi K, Ueno T, Takano T, Ohno S, Takahashi S. Fukada I, et al. Among authors: osako t. Sci Rep. 2022 Mar 21;12(1):4813. doi: 10.1038/s41598-022-08925-3. Sci Rep. 2022. PMID: 35315838 Free PMC article.
180 results