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Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus.
Yin X, Kim K, Suetsugu H, Bang SY, Wen L, Koido M, Ha E, Liu L, Sakamoto Y, Jo S, Leng RX, Otomo N, Laurynenka V, Kwon YC, Sheng Y, Sugano N, Hwang MY, Li W, Mukai M, Yoon K, Cai M, Ishigaki K, Chung WT, Huang H, Takahashi D, Lee SS, Wang M, Karino K, Shim SC, Zheng X, Miyamura T, Kang YM, Ye D, Nakamura J, Suh CH, Tang Y, Motomura G, Park YB, Ding H, Kuroda T, Choe JY, Li C, Niiro H, Park Y, Shen C, Miyamoto T, Ahn GY, Fei W, Takeuchi T, Shin JM, Li K, Kawaguchi Y, Lee YK, Wang Y, Amano K, Park DJ, Yang W, Tada Y, Yamaji K, Shimizu M, Atsumi T, Suzuki A, Sumida T, Okada Y, Matsuda K, Matsuo K, Kochi Y; Japanese Research Committee on Idiopathic Osteonecrosis of the Femoral Head; Kottyan LC, Weirauch MT, Parameswaran S, Eswar S, Salim H, Chen X, Yamamoto K, Harley JB, Ohmura K, Kim TH, Yang S, Yamamoto T, Kim BJ, Shen N, Ikegawa S, Lee HS, Zhang X, Terao C, Cui Y, Bae SC. Yin X, et al. Among authors: otomo n. Ann Rheum Dis. 2021 May;80(5):632-640. doi: 10.1136/annrheumdis-2020-219209. Epub 2020 Dec 3. Ann Rheum Dis. 2021. PMID: 33272962 Free PMC article.
Genome-wide meta-analysis and replication studies in multiple ethnicities identify novel adolescent idiopathic scoliosis susceptibility loci.
Khanshour AM, Kou I, Fan Y, Einarsdottir E, Makki N, Kidane YH, Kere J, Grauers A, Johnson TA, Paria N, Patel C, Singhania R, Kamiya N, Takeda K, Otomo N, Watanabe K, Luk KDK, Cheung KMC, Herring JA, Rios JJ, Ahituv N, Gerdhem P, Gurnett CA, Song YQ, Ikegawa S, Wise CA. Khanshour AM, et al. Among authors: otomo n. Hum Mol Genet. 2018 Nov 15;27(22):3986-3998. doi: 10.1093/hmg/ddy306. Hum Mol Genet. 2018. PMID: 30395268 Free PMC article.
A multiethnic meta-analysis defined the association of rs12946942 with severe adolescent idiopathic scoliosis.
Takeda K, Kou I, Otomo N, Grauers A, Fan YH, Ogura Y, Takahashi Y, Momozawa Y, Einarsdottir E, Kere J; Japan Scoliosis Clinical Research Group (JSCRG); Matsumoto M, Qiu Y, Song YQ, Gerdhem P, Watanabe K, Ikegawa S. Takeda K, et al. Among authors: otomo n. J Hum Genet. 2019 May;64(5):493-498. doi: 10.1038/s10038-019-0575-7. Epub 2019 Feb 21. J Hum Genet. 2019. PMID: 30787423
Association of Susceptibility Genes for Adolescent Idiopathic Scoliosis and Intervertebral Disc Degeneration With Adult Spinal Deformity.
Takeda K, Kou I, Hosogane N, Otomo N, Yagi M, Kaneko S, Kono H, Ishikawa M, Takahashi Y, Ikegami T, Nojiri K, Okada E, Funao H, Okuyama K, Tsuji T, Fujita N, Nagoshi N, Tsuji O, Ogura Y, Ishii K, Nakamura M, Matsumoto M, Ikegawa S, Watanabe K. Takeda K, et al. Among authors: otomo n. Spine (Phila Pa 1976). 2019 Dec 1;44(23):1623-1629. doi: 10.1097/BRS.0000000000003179. Spine (Phila Pa 1976). 2019. PMID: 31365516
Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese.
Kou I, Otomo N, Takeda K, Momozawa Y, Lu HF, Kubo M, Kamatani Y, Ogura Y, Takahashi Y, Nakajima M, Minami S, Uno K, Kawakami N, Ito M, Yonezawa I, Watanabe K, Kaito T, Yanagida H, Taneichi H, Harimaya K, Taniguchi Y, Shigematsu H, Iida T, Demura S, Sugawara R, Fujita N, Yagi M, Okada E, Hosogane N, Kono K, Nakamura M, Chiba K, Kotani T, Sakuma T, Akazawa T, Suzuki T, Nishida K, Kakutani K, Tsuji T, Sudo H, Iwata A, Sato T, Inami S, Matsumoto M, Terao C, Watanabe K, Ikegawa S. Kou I, et al. Among authors: otomo n. Nat Commun. 2019 Aug 15;10(1):3685. doi: 10.1038/s41467-019-11596-w. Nat Commun. 2019. PMID: 31417091 Free PMC article.
Eight novel susceptibility loci and putative causal variants in atopic dermatitis.
Tanaka N, Koido M, Suzuki A, Otomo N, Suetsugu H, Kochi Y, Tomizuka K, Momozawa Y, Kamatani Y; Biobank Japan Project; Ikegawa S, Yamamoto K, Terao C. Tanaka N, et al. Among authors: otomo n. J Allergy Clin Immunol. 2021 Nov;148(5):1293-1306. doi: 10.1016/j.jaci.2021.04.019. Epub 2021 Jun 8. J Allergy Clin Immunol. 2021. PMID: 34116867
Polygenic Risk Score of Adolescent Idiopathic Scoliosis for Potential Clinical Use.
Otomo N, Lu HF, Koido M, Kou I, Takeda K, Momozawa Y, Kubo M, Kamatani Y, Ogura Y, Takahashi Y, Nakajima M, Minami S, Uno K, Kawakami N, Ito M, Sato T, Watanabe K, Kaito T, Yanagida H, Taneichi H, Harimaya K, Taniguchi Y, Shigematsu H, Iida T, Demura S, Sugawara R, Fujita N, Yagi M, Okada E, Hosogane N, Kono K, Nakamura M, Chiba K, Kotani T, Sakuma T, Akazawa T, Suzuki T, Nishida K, Kakutani K, Tsuji T, Sudo H, Iwata A, Kaneko K, Inami S, Kochi Y, Chang WC, Matsumoto M, Watanabe K, Ikegawa S, Terao C. Otomo N, et al. J Bone Miner Res. 2021 Aug;36(8):1481-1491. doi: 10.1002/jbmr.4324. Epub 2021 Jun 22. J Bone Miner Res. 2021. PMID: 34159637 Free article.
69 results