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Page 1
Genetic determinants of circulating GIP and GLP-1 concentrations.
Almgren P, Lindqvist A, Krus U, Hakaste L, Ottosson-Laakso E, Asplund O, Sonestedt E, Prasad RB, Laurila E, Orho-Melander M, Melander O, Tuomi T, Holst JJ, Nilsson PM, Wierup N, Groop L, Ahlqvist E. Almgren P, et al. Among authors: ottosson laakso e. JCI Insight. 2017 Nov 2;2(21):e93306. doi: 10.1172/jci.insight.93306. JCI Insight. 2017. PMID: 29093273 Free PMC article.
SCRT1 is a novel beta cell transcription factor with insulin regulatory properties.
Chriett S, Lindqvist A, Shcherbina L, Edlund A, Abels M, Asplund O, Martínez López JA, Ottosson-Laakso E, Hatem G, Prasad RB, Groop L, Eliasson L, Hansson O, Wierup N. Chriett S, et al. Among authors: ottosson laakso e. Mol Cell Endocrinol. 2021 Feb 5;521:111107. doi: 10.1016/j.mce.2020.111107. Epub 2020 Dec 10. Mol Cell Endocrinol. 2021. PMID: 33309639
Islet Gene View-a tool to facilitate islet research.
Asplund O, Storm P, Chandra V, Hatem G, Ottosson-Laakso E, Mansour-Aly D, Krus U, Ibrahim H, Ahlqvist E, Tuomi T, Renström E, Korsgren O, Wierup N, Ibberson M, Solimena M, Marchetti P, Wollheim C, Artner I, Mulder H, Hansson O, Otonkoski T, Groop L, Prasad RB. Asplund O, et al. Among authors: ottosson laakso e. Life Sci Alliance. 2022 Aug 10;5(12):e202201376. doi: 10.26508/lsa.202201376. Life Sci Alliance. 2022. PMID: 35948367 Free PMC article.
Serotonin (5-HT) receptor 2b activation augments glucose-stimulated insulin secretion in human and mouse islets of Langerhans.
Bennet H, Mollet IG, Balhuizen A, Medina A, Nagorny C, Bagge A, Fadista J, Ottosson-Laakso E, Vikman P, Dekker-Nitert M, Eliasson L, Wierup N, Artner I, Fex M. Bennet H, et al. Among authors: ottosson laakso e. Diabetologia. 2016 Apr;59(4):744-54. doi: 10.1007/s00125-015-3847-6. Epub 2016 Jan 6. Diabetologia. 2016. PMID: 26733006
TCF7L2 is a master regulator of insulin production and processing.
Zhou Y, Park SY, Su J, Bailey K, Ottosson-Laakso E, Shcherbina L, Oskolkov N, Zhang E, Thevenin T, Fadista J, Bennet H, Vikman P, Wierup N, Fex M, Rung J, Wollheim C, Nobrega M, Renström E, Groop L, Hansson O. Zhou Y, et al. Hum Mol Genet. 2014 Dec 15;23(24):6419-31. doi: 10.1093/hmg/ddu359. Epub 2014 Jul 11. Hum Mol Genet. 2014. PMID: 25015099 Free PMC article.
14 results