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Interplay between Immune Checkpoint Proteins and Cellular Metabolism.
Lim S, Phillips JB, Madeira da Silva L, Zhou M, Fodstad O, Owen LB, Tan M. Lim S, et al. Among authors: owen lb. Cancer Res. 2017 Mar 15;77(6):1245-1249. doi: 10.1158/0008-5472.CAN-16-1647. Epub 2017 Feb 28. Cancer Res. 2017. PMID: 28246276 Free PMC article. Review.
An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor κB- and hypoxia-inducible factor 1α-mediated up-regulation of CXCR4.
Arora S, Bhardwaj A, Singh S, Srivastava SK, McClellan S, Nirodi CS, Piazza GA, Grizzle WE, Owen LB, Singh AP. Arora S, et al. Among authors: owen lb. J Biol Chem. 2013 Jul 19;288(29):21197-21207. doi: 10.1074/jbc.M113.484576. Epub 2013 Jun 5. J Biol Chem. 2013. PMID: 23740244 Free PMC article.
CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated activation of nuclear factor κB: implications for bidirectional tumor-stromal interactions.
Singh AP, Arora S, Bhardwaj A, Srivastava SK, Kadakia MP, Wang B, Grizzle WE, Owen LB, Singh S. Singh AP, et al. Among authors: owen lb. J Biol Chem. 2012 Nov 9;287(46):39115-24. doi: 10.1074/jbc.M112.409581. Epub 2012 Sep 20. J Biol Chem. 2012. PMID: 22995914 Free PMC article.
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