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Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Morón FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MW, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuiness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Deniz Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F; European Alzheimer's Disease Initiative (EADI); Genetic and Environmental Risk in Alzheimer's Disease; Alzheimer's Disease Genetic Consortium; Cohorts for Heart and Aging Research in Genomic Epidemiology; Moebus S, Mecocci P, Del Zo… See abstract for full author list ➔ Lambert JC, et al. Among authors: owen mj. Nat Genet. 2013 Dec;45(12):1452-8. doi: 10.1038/ng.2802. Epub 2013 Oct 27. Nat Genet. 2013. PMID: 24162737 Free PMC article.
Looking for genes in schizophrenia.
Owen MJ, Gill M. Owen MJ, et al. Clin Neuropharmacol. 1992;15 Suppl 1 Pt A:222A-223A. doi: 10.1097/00002826-199201001-00116. Clin Neuropharmacol. 1992. PMID: 1498819 No abstract available.
Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder.
St George-Hyslop PH, Haines JL, Farrer LA, Polinsky R, Van Broeckhoven C, Goate A, McLachlan DR, Orr H, Bruni AC, Sorbi S, Rainero I, Foncin JF, Pollen D, Cantu JM, Tupler R, Voskresenskaya N, Mayeux R, Growden J, Fried VA, Myers RH, Nee L, Backhovens H, Martin JJ, Rossor M, Owen MJ, Mullan M, Percy ME, Karlinsky H, Rich S, Heston L, Montesi M, Mortilla M, Nacmias N, Gusella JF, Hardy JA; FAD Collaborative Study Group, et al. St George-Hyslop PH, et al. Among authors: owen mj. Nature. 1990 Sep 13;347(6289):194-7. doi: 10.1038/347194a0. Nature. 1990. PMID: 2395471
Genetics of Alzheimer's disease.
Goate AM, Hardy JA, Owen MJ, Haynes A, James L, Farrall M, Mullan MJ, Roques P, Rossor MN. Goate AM, et al. Among authors: owen mj. Adv Neurol. 1990;51:197-8. Adv Neurol. 1990. PMID: 2403711 Review. No abstract available.
Molecular genetics of Alzheimer's disease.
Hardy JA, Owen MJ, Goate AM, James LA, Haynes AR, Rossor MN, Roques P, Mullan MJ. Hardy JA, et al. Among authors: owen mj. Biochem Soc Trans. 1989 Feb;17(1):75-6. doi: 10.1042/bst0170075. Biochem Soc Trans. 1989. PMID: 2523829 Review. No abstract available.
Predisposing locus for Alzheimer's disease on chromosome 21.
Goate AM, Haynes AR, Owen MJ, Farrall M, James LA, Lai LY, Mullan MJ, Roques P, Rossor MN, Williamson R, et al. Goate AM, et al. Among authors: owen mj. Lancet. 1989 Feb 18;1(8634):352-5. doi: 10.1016/s0140-6736(89)91725-x. Lancet. 1989. PMID: 2563508
Modelling the occurrence and pathology of Alzheimer's disease.
Hardy JA, Goate AM, Owen MJ, Mullan MJ, Rossor MN, Pearson RC. Hardy JA, et al. Among authors: owen mj. Neurobiol Aging. 1989 Sep-Oct;10(5):429-31; discussion 446-8. doi: 10.1016/0197-4580(89)90084-5. Neurobiol Aging. 1989. PMID: 2812201
1,096 results