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Page 1
A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.
Petersen GM, Amundadottir L, Fuchs CS, Kraft P, Stolzenberg-Solomon RZ, Jacobs KB, Arslan AA, Bueno-de-Mesquita HB, Gallinger S, Gross M, Helzlsouer K, Holly EA, Jacobs EJ, Klein AP, LaCroix A, Li D, Mandelson MT, Olson SH, Risch HA, Zheng W, Albanes D, Bamlet WR, Berg CD, Boutron-Ruault MC, Buring JE, Bracci PM, Canzian F, Clipp S, Cotterchio M, de Andrade M, Duell EJ, Gaziano JM, Giovannucci EL, Goggins M, Hallmans G, Hankinson SE, Hassan M, Howard B, Hunter DJ, Hutchinson A, Jenab M, Kaaks R, Kooperberg C, Krogh V, Kurtz RC, Lynch SM, McWilliams RR, Mendelsohn JB, Michaud DS, Parikh H, Patel AV, Peeters PH, Rajkovic A, Riboli E, Rodriguez L, Seminara D, Shu XO, Thomas G, Tjønneland A, Tobias GS, Trichopoulos D, Van Den Eeden SK, Virtamo J, Wactawski-Wende J, Wang Z, Wolpin BM, Yu H, Yu K, Zeleniuch-Jacquotte A, Fraumeni JF Jr, Hoover RN, Hartge P, Chanock SJ. Petersen GM, et al. Nat Genet. 2010 Mar;42(3):224-8. doi: 10.1038/ng.522. Epub 2010 Jan 24. Nat Genet. 2010. PMID: 20101243 Free PMC article.
Importance of age of onset in pancreatic cancer kindreds.
Brune KA, Lau B, Palmisano E, Canto M, Goggins MG, Hruban RH, Klein AP. Brune KA, et al. J Natl Cancer Inst. 2010 Jan 20;102(2):119-26. doi: 10.1093/jnci/djp466. Epub 2010 Jan 12. J Natl Cancer Inst. 2010. PMID: 20068195 Free PMC article.
Elevated cancer mortality in the relatives of patients with pancreatic cancer.
Wang L, Brune KA, Visvanathan K, Laheru D, Herman J, Wolfgang C, Schulick R, Cameron JL, Goggins M, Hruban RH, Klein AP. Wang L, et al. Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):2829-34. doi: 10.1158/1055-9965.EPI-09-0557. Epub 2009 Oct 20. Cancer Epidemiol Biomarkers Prev. 2009. PMID: 19843679 Free PMC article.
Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer.
Amundadottir L, Kraft P, Stolzenberg-Solomon RZ, Fuchs CS, Petersen GM, Arslan AA, Bueno-de-Mesquita HB, Gross M, Helzlsouer K, Jacobs EJ, LaCroix A, Zheng W, Albanes D, Bamlet W, Berg CD, Berrino F, Bingham S, Buring JE, Bracci PM, Canzian F, Clavel-Chapelon F, Clipp S, Cotterchio M, de Andrade M, Duell EJ, Fox JW Jr, Gallinger S, Gaziano JM, Giovannucci EL, Goggins M, González CA, Hallmans G, Hankinson SE, Hassan M, Holly EA, Hunter DJ, Hutchinson A, Jackson R, Jacobs KB, Jenab M, Kaaks R, Klein AP, Kooperberg C, Kurtz RC, Li D, Lynch SM, Mandelson M, McWilliams RR, Mendelsohn JB, Michaud DS, Olson SH, Overvad K, Patel AV, Peeters PH, Rajkovic A, Riboli E, Risch HA, Shu XO, Thomas G, Tobias GS, Trichopoulos D, Van Den Eeden SK, Virtamo J, Wactawski-Wende J, Wolpin BM, Yu H, Yu K, Zeleniuch-Jacquotte A, Chanock SJ, Hartge P, Hoover RN. Amundadottir L, et al. Nat Genet. 2009 Sep;41(9):986-90. doi: 10.1038/ng.429. Epub 2009 Aug 2. Nat Genet. 2009. PMID: 19648918 Free PMC article.
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene.
Jones S, Hruban RH, Kamiyama M, Borges M, Zhang X, Parsons DW, Lin JC, Palmisano E, Brune K, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Parmigiani G, Kern SE, Velculescu VE, Kinzler KW, Vogelstein B, Eshleman JR, Goggins M, Klein AP. Jones S, et al. Science. 2009 Apr 10;324(5924):217. doi: 10.1126/science.1171202. Epub 2009 Mar 5. Science. 2009. PMID: 19264984 Free PMC article.
Allele-specific expression in the germline of patients with familial pancreatic cancer: an unbiased approach to cancer gene discovery.
Tan AC, Fan JB, Karikari C, Bibikova M, Garcia EW, Zhou L, Barker D, Serre D, Feldmann G, Hruban RH, Klein AP, Goggins M, Couch FJ, Hudson TJ, Winslow RL, Maitra A, Chakravarti A. Tan AC, et al. Cancer Biol Ther. 2008 Jan;7(1):135-44. doi: 10.4161/cbt.7.1.5199. Epub 2007 Oct 19. Cancer Biol Ther. 2008. PMID: 18059179 Free PMC article.