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Overcoming resistance to Sonic Hedgehog inhibition by targeting p90 ribosomal S6 kinase in pediatric medulloblastoma.
Pediatr Blood Cancer. 2014 Jan;61(1):107-15. doi: 10.1002/pbc.24675. Epub 2013 Aug 12.
Pediatr Blood Cancer. 2014.
PMID: 23940083
Personalizing the treatment of pediatric medulloblastoma: Polo-like kinase 1 as a molecular target in high-risk children.
Triscott J, Lee C, Foster C, Manoranjan B, Pambid MR, Berns R, Fotovati A, Venugopal C, O'Halloran K, Narendran A, Hawkins C, Ramaswamy V, Bouffet E, Taylor MD, Singhal A, Hukin J, Rassekh R, Yip S, Northcott P, Singh SK, Dunham C, Dunn SE.
Triscott J, et al. Among authors: pambid mr.
Cancer Res. 2013 Nov 15;73(22):6734-44. doi: 10.1158/0008-5472.CAN-12-4331. Epub 2013 Sep 9.
Cancer Res. 2013.
PMID: 24019381
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Disulfiram, a drug widely used to control alcoholism, suppresses the self-renewal of glioblastoma and over-rides resistance to temozolomide.
Triscott J, Lee C, Hu K, Fotovati A, Berns R, Pambid M, Luk M, Kast RE, Kong E, Toyota E, Yip S, Toyota B, Dunn SE.
Triscott J, et al.
Oncotarget. 2012 Oct;3(10):1112-23. doi: 10.18632/oncotarget.604.
Oncotarget. 2012.
PMID: 23047041
Free PMC article.
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RSK2: a promising therapeutic target for the treatment of triple-negative breast cancer.
Huynh MM, Jayanthan A, Pambid MR, Los G, Dunn SE.
Huynh MM, et al. Among authors: pambid mr.
Expert Opin Ther Targets. 2020 Jan;24(1):1-5. doi: 10.1080/14728222.2020.1709824. Epub 2019 Dec 27.
Expert Opin Ther Targets. 2020.
PMID: 31875730
No abstract available.
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YB-1 transforms human mammary epithelial cells through chromatin remodeling leading to the development of basal-like breast cancer.
Davies AH, Reipas KM, Pambid MR, Berns R, Stratford AL, Fotovati A, Firmino N, Astanehe A, Hu K, Maxwell C, Mills GB, Dunn SE.
Davies AH, et al. Among authors: pambid mr.
Stem Cells. 2014 Jun;32(6):1437-50. doi: 10.1002/stem.1707.
Stem Cells. 2014.
PMID: 24648416
Free PMC article.
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YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction and HER2 amplification.
Davies AH, Barrett I, Pambid MR, Hu K, Stratford AL, Freeman S, Berquin IM, Pelech S, Hieter P, Maxwell C, Dunn SE.
Davies AH, et al. Among authors: pambid mr.
Oncogene. 2011 Aug 25;30(34):3649-60. doi: 10.1038/onc.2011.82. Epub 2011 Mar 21.
Oncogene. 2011.
PMID: 21423216
Free PMC article.
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The dawn of targeted therapies for triple negative breast cancer (TNBC): a snapshot of investigational drugs in phase I and II trials.
Huynh MM, Pambid MR, Jayanthan A, Dorr A, Los G, Dunn SE.
Huynh MM, et al. Among authors: pambid mr.
Expert Opin Investig Drugs. 2020 Nov;29(11):1199-1208. doi: 10.1080/13543784.2020.1818067. Epub 2020 Sep 17.
Expert Opin Investig Drugs. 2020.
PMID: 32869671
Review.
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