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Liver receptor homolog-1 is a critical determinant of methyl-pool metabolism.
Wagner M, Choi S, Panzitt K, Mamrosh JL, Lee JM, Zaufel A, Xiao R, Wooton-Kee R, Ståhlman M, Newgard CB, Borén J, Moore DD. Wagner M, et al. Among authors: panzitt k. Hepatology. 2016 Jan;63(1):95-106. doi: 10.1002/hep.28124. Epub 2015 Oct 10. Hepatology. 2016. PMID: 26267291 Free PMC article.
Bile acids increase steroidogenesis in cholemic mice and induce cortisol secretion in adrenocortical H295R cells via S1PR2, ERK and SF-1.
Liu L, Panzitt K, Racedo S, Wagner M, Platzer W, Zaufel A, Theiler-Schwetz V, Obermayer-Pietsch B, Müller H, Höfler G, Heinemann A, Zollner G, Fickert P. Liu L, et al. Among authors: panzitt k. Liver Int. 2019 Nov;39(11):2112-2123. doi: 10.1111/liv.14052. Epub 2019 Feb 17. Liver Int. 2019. PMID: 30664326 Free PMC article.
FXR-dependent Rubicon induction impairs autophagy in models of human cholestasis.
Panzitt K, Jungwirth E, Krones E, Lee JM, Pollheimer M, Thallinger GG, Kolb-Lenz D, Xiao R, Thorell A, Trauner M, Fickert P, Marschall HU, Moore DD, Wagner M. Panzitt K, et al. J Hepatol. 2020 Jun;72(6):1122-1131. doi: 10.1016/j.jhep.2020.01.014. Epub 2020 Jan 28. J Hepatol. 2020. PMID: 32001325 Free article.
Bile acid-induced tissue factor activity in hepatocytes correlates with activation of farnesoid X receptor.
Greimel T, Jahnel J, Pohl S, Strini T, Tischitz M, Meier-Allard N, Holasek S, Meinel K, Aguiriano-Moser V, Zobel J, Haidl H, Gallistl S, Panzitt K, Wagner M, Schlagenhauf A. Greimel T, et al. Among authors: panzitt k. Lab Invest. 2021 Oct;101(10):1394-1402. doi: 10.1038/s41374-021-00628-z. Epub 2021 Jun 18. Lab Invest. 2021. PMID: 34145381 Free PMC article.
Recent advances on FXR-targeting therapeutics.
Panzitt K, Zollner G, Marschall HU, Wagner M. Panzitt K, et al. Mol Cell Endocrinol. 2022 Jul 15;552:111678. doi: 10.1016/j.mce.2022.111678. Epub 2022 May 20. Mol Cell Endocrinol. 2022. PMID: 35605722 Free article. Review.
19 results