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Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement.
Zhang N, Lin C, Huang X, Kolbanovskiy A, Hingerty BE, Amin S, Broyde S, Geacintov NE, Patel DJ. Zhang N, et al. Among authors: patel dj. J Mol Biol. 2005 Mar 4;346(4):951-65. doi: 10.1016/j.jmb.2004.12.027. Epub 2004 Dec 31. J Mol Biol. 2005. PMID: 15701509 Free PMC article.
659 results