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Dihydroxythiophenes are novel potent inhibitors of human immunodeficiency virus integrase with a diketo acid-like pharmacophore.
Kehlenbeck S, Betz U, Birkmann A, Fast B, Göller AH, Henninger K, Lowinger T, Marrero D, Paessens A, Paulsen D, Pevzner V, Schohe-Loop R, Tsujishita H, Welker R, Kreuter J, Rübsamen-Waigmann H, Dittmer F. Kehlenbeck S, et al. Among authors: paulsen d. J Virol. 2006 Jul;80(14):6883-94. doi: 10.1128/JVI.00306-06. J Virol. 2006. PMID: 16809294 Free PMC article.
Pharmacokinetics-pharmacodynamics of the helicase-primase inhibitor pritelivir following treatment of wild-type or pritelivir-resistant virus infection in a murine herpes simplex virus 1 infection model.
Biswas S, Sukla S, Goldner T, Field HJ, Kropeit D, Paulsen D, Welbers A, Ruebsamen-Schaeff H, Zimmermann H, Birkmann A. Biswas S, et al. Among authors: paulsen d. Antimicrob Agents Chemother. 2014 Jul;58(7):3843-52. doi: 10.1128/AAC.02641-14. Epub 2014 Apr 21. Antimicrob Agents Chemother. 2014. PMID: 24752278 Free PMC article.
Development and optimisation of a procedure for the production of Parapoxvirus ovis by large-scale microcarrier cell culture in a non-animal, non-human and non-plant-derived medium.
Pohlscheidt M, Langer U, Minuth T, Bödeker B, Apeler H, Hörlein HD, Paulsen D, Rübsamen-Waigmann H, Henzler HJ, Reichl U. Pohlscheidt M, et al. Among authors: paulsen d. Vaccine. 2008 Mar 17;26(12):1552-65. doi: 10.1016/j.vaccine.2008.01.032. Epub 2008 Feb 5. Vaccine. 2008. PMID: 18295380
In vitro and in vivo activities of the novel anticytomegalovirus compound AIC246.
Lischka P, Hewlett G, Wunberg T, Baumeister J, Paulsen D, Goldner T, Ruebsamen-Schaeff H, Zimmermann H. Lischka P, et al. Among authors: paulsen d. Antimicrob Agents Chemother. 2010 Mar;54(3):1290-7. doi: 10.1128/AAC.01596-09. Epub 2010 Jan 4. Antimicrob Agents Chemother. 2010. PMID: 20047911 Free PMC article.
172 results