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Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus.
Ansari MA, Pedergnana V, L C Ip C, Magri A, Von Delft A, Bonsall D, Chaturvedi N, Bartha I, Smith D, Nicholson G, McVean G, Trebes A, Piazza P, Fellay J, Cooke G, Foster GR; STOP-HCV Consortium; Hudson E, McLauchlan J, Simmonds P, Bowden R, Klenerman P, Barnes E, Spencer CCA. Ansari MA, et al. Among authors: pedergnana v. Nat Genet. 2017 May;49(5):666-673. doi: 10.1038/ng.3835. Epub 2017 Apr 10. Nat Genet. 2017. PMID: 28394351 Free PMC article.
Interferon lambda 4 impacts the genetic diversity of hepatitis C virus.
Ansari MA, Aranday-Cortes E, Ip CL, da Silva Filipe A, Lau SH, Bamford C, Bonsall D, Trebes A, Piazza P, Sreenu V, Cowton VM; STOP-HCV Consortium; Hudson E, Bowden R, Patel AH, Foster GR, Irving WL, Agarwal K, Thomson EC, Simmonds P, Klenerman P, Holmes C, Barnes E, Spencer CC, McLauchlan J, Pedergnana V. Ansari MA, et al. Among authors: pedergnana v. Elife. 2019 Sep 3;8:e42463. doi: 10.7554/eLife.42463. Elife. 2019. PMID: 31478835 Free PMC article.
Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure.
Smith DA, Fernandez-Antunez C, Magri A, Bowden R, Chaturvedi N, Fellay J, McLauchlan J, Foster GR, Irving WL; STOP-HCV Consortium; Simmonds P, Pedergnana V, Ramirez S, Bukh J, Barnes E, Ansari MA. Smith DA, et al. Among authors: pedergnana v. Nat Commun. 2021 Oct 20;12(1):6105. doi: 10.1038/s41467-021-25649-6. Nat Commun. 2021. PMID: 34671027 Free PMC article.
Comprehensive Comparative Analysis of Standard Validated, Genetic, and Novel Biomarkers to Enhance Prognostic Risk-Stratification in Patients With Hepatitis C Virus Cirrhosis.
Innes H, Walker AJ, Benselin J, Grove JI, Pedergnana V, Azim Ansari M, Lin SK, McLauchlan J, Hutchinson SJ, Barnes E, Irving WL, Guha IN; on behalf of the HCV Research UK; & STOP-HCV; Consortia. Innes H, et al. Among authors: pedergnana v. Clin Transl Gastroenterol. 2022 Feb 9;13(3):e00462. doi: 10.14309/ctg.0000000000000462. Clin Transl Gastroenterol. 2022. PMID: 35142723 Free PMC article.
Genome-Wide Association Study for Alcohol-Related Cirrhosis Identifies Risk Loci in MARC1 and HNRNPUL1.
Innes H, Buch S, Hutchinson S, Guha IN, Morling JR, Barnes E, Irving W, Forrest E, Pedergnana V, Goldberg D, Aspinall E, Barclay S, Hayes PC, Dillon J, Nischalke HD, Lutz P, Spengler U, Fischer J, Berg T, Brosch M, Eyer F, Datz C, Mueller S, Peccerella T, Deltenre P, Marot A, Soyka M, McQuillin A, Morgan MY, Hampe J, Stickel F. Innes H, et al. Among authors: pedergnana v. Gastroenterology. 2020 Oct;159(4):1276-1289.e7. doi: 10.1053/j.gastro.2020.06.014. Epub 2020 Jun 16. Gastroenterology. 2020. PMID: 32561361
The rs429358 Locus in Apolipoprotein E Is Associated With Hepatocellular Carcinoma in Patients With Cirrhosis.
Innes H, Nischalke HD, Guha IN, Weiss KH, Irving W, Gotthardt D, Barnes E, Fischer J, Ansari MA, Rosendahl J, Lin SK, Marot A, Pedergnana V, Casper M, Benselin J, Lammert F, McLauchlan J, Lutz PL, Hamill V, Mueller S, Morling JR, Semmler G, Eyer F, von Felden J, Link A, Vogel A, Marquardt JU, Sulk S, Trebicka J, Valenti L, Datz C, Reiberger T, Schafmayer C, Berg T, Deltenre P, Hampe J, Stickel F, Buch S. Innes H, et al. Among authors: pedergnana v. Hepatol Commun. 2022 May;6(5):1213-1226. doi: 10.1002/hep4.1886. Epub 2021 Dec 27. Hepatol Commun. 2022. PMID: 34958182 Free PMC article.
38 results