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Pharmacokinetic and Pharmacodynamic Evaluation following Vaginal Application of IQB3002, a Dual-Chamber Microbicide Gel Containing the Nonnucleoside Reverse Transcriptase Inhibitor IQP-0528 in Rhesus Macaques.
Pereira LE, Mesquita PM, Ham A, Singletary T, Deyounks F, Martin A, McNicholl J, Buckheit KW, Buckheit RW Jr, Smith JM. Pereira LE, et al. Antimicrob Agents Chemother. 2015 Dec 14;60(3):1393-400. doi: 10.1128/AAC.02201-15. Antimicrob Agents Chemother. 2015. PMID: 26666935 Free PMC article.
Effects of gel volume on pharmacokinetics for vaginal and rectal applications of combination DuoGel-IQB4012, a dual chamber-dual drug HIV microbicide gel, in pigtailed macaques.
Pereira LE, Singletary T, Martin A, Dinh CT, Deyounks F, Holder A, McNicholl J, Buckheit KW, Buckheit RW Jr, Ham A, Katz DF, Smith JM. Pereira LE, et al. Drug Deliv Transl Res. 2018 Oct;8(5):1180-1190. doi: 10.1007/s13346-018-0538-0. Drug Deliv Transl Res. 2018. PMID: 29761350 Free PMC article.
A polyvalent Clade B virus-like particle HIV vaccine combined with partially protective oral preexposure prophylaxis prevents simian-human immunodeficiency virus Infection in macaques and primes for virus-amplified immunity.
Ross TM, Pereira LE, Luckay A, McNicholl JM, García-Lerma JG, Heneine W, Eugene HS, Pierce-Paul BR, Zhang J, Hendry RM, Smith JM. Ross TM, et al. Among authors: pereira le. AIDS Res Hum Retroviruses. 2014 Nov;30(11):1072-81. doi: 10.1089/AID.2014.0030. Epub 2014 Jul 29. AIDS Res Hum Retroviruses. 2014. PMID: 24914761 Free PMC article.
Sexually transmitted infections and depot medroxyprogesterone acetate do not impact protection from simian HIV acquisition by long-acting cabotegravir in macaques.
Vishwanathan SA, Zhao C, Luthra R, Khalil GK, Morris MM, Dinh C, Gary MJ, Mitchell J, Spreen WR, Pereira LE, Heneine W, García-Lerma JG, McNicholl JM. Vishwanathan SA, et al. Among authors: pereira le. AIDS. 2022 Feb 1;36(2):169-176. doi: 10.1097/QAD.0000000000003059. AIDS. 2022. PMID: 34482355 Free PMC article.
Increases in Endogenous or Exogenous Progestins Promote Virus-Target Cell Interactions within the Non-human Primate Female Reproductive Tract.
Carias AM, Allen SA, Fought AJ, Kotnik Halavaty K, Anderson MR, Jimenez ML, McRaven MD, Gioia CJ, Henning TR, Kersh EN, Smith JM, Pereira LE, Butler K, McNicholl SJ, Hendry RM, Kiser PF, Veazey RS, Hope TJ. Carias AM, et al. Among authors: pereira le. PLoS Pathog. 2016 Sep 22;12(9):e1005885. doi: 10.1371/journal.ppat.1005885. eCollection 2016 Sep. PLoS Pathog. 2016. PMID: 27658293 Free PMC article.
A Nonhuman Primate Model for Rectally Transmitted Syphilis.
Tansey C, Zhao C, Hopkins A, Ritter JM, Fakile YF, Pillay A, Katz SS, Pereira L, Mitchell J, Deyounks F, Kersh EN, McNicholl JM, Vishwanathan SA. Tansey C, et al. J Infect Dis. 2018 Mar 13;217(7):1139-1144. doi: 10.1093/infdis/jix669. J Infect Dis. 2018. PMID: 29309603 Free PMC article.
Hydroxyproline metabolism enhances IFN-γ-induced PD-L1 expression and inhibits autophagic flux.
Spangenberg SH, Palermo A, Gazaniga NR, Martínez-Peña F, Guijas C, Chin EN, Rinschen MM, Sander PN, Webb B, Pereira LE, Jia Y, Meitz L, Siuzdak G, Lairson LL. Spangenberg SH, et al. Among authors: pereira le. Cell Chem Biol. 2023 Sep 21;30(9):1115-1134.e10. doi: 10.1016/j.chembiol.2023.06.016. Epub 2023 Jul 18. Cell Chem Biol. 2023. PMID: 37467751
55 results