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Potential SARS-CoV-2 main protease inhibitors.
Banerjee R, Perera L, Tillekeratne LMV. Banerjee R, et al. Among authors: perera l. Drug Discov Today. 2021 Mar;26(3):804-816. doi: 10.1016/j.drudis.2020.12.005. Epub 2020 Dec 9. Drug Discov Today. 2021. PMID: 33309533 Free PMC article. Review.
A new class of cytotoxic agents targets tubulin and disrupts microtubule dynamics.
Al-Hamashi AA, Koranne R, Dlamini S, Alqahtani A, Karaj E, Rashid MS, Knoff JR, Dunworth M, Pflum MKH, Casero RA Jr, Perera L, Taylor WR, Tillekeratne LMV. Al-Hamashi AA, et al. Among authors: perera l. Bioorg Chem. 2021 Nov;116:105297. doi: 10.1016/j.bioorg.2021.105297. Epub 2021 Aug 30. Bioorg Chem. 2021. PMID: 34509798 Free PMC article.
A humanized nanobody phage display library yields potent binders of SARS CoV-2 spike.
Fu Y, da Fonseca Rezende E Mello J, Fleming BD, Renn A, Chen CZ, Hu X, Xu M, Gorshkov K, Hanson Q, Zheng W, Lee EM, Perera L, Petrovich R, Pradhan M, Eastman RT, Itkin Z, Stanley TB, Hsu A, Dandey V, Sharma K, Gillette W, Taylor T, Ramakrishnan N, Perkins S, Esposito D, Oh E, Susumu K, Wolak M, Ferrer M, Hall MD, Borgnia MJ, Simeonov A. Fu Y, et al. Among authors: perera l. PLoS One. 2022 Aug 10;17(8):e0272364. doi: 10.1371/journal.pone.0272364. eCollection 2022. PLoS One. 2022. PMID: 35947606 Free PMC article.
Cryo-EM Structures of the SARS-CoV-2 Endoribonuclease Nsp15.
Pillon MC, Frazier MN, Dillard LB, Williams JG, Kocaman S, Krahn JM, Perera L, Hayne CK, Gordon J, Stewart ZD, Sobhany M, Deterding LJ, Hsu AL, Dandey VP, Borgnia MJ, Stanley RE. Pillon MC, et al. Among authors: perera l. bioRxiv [Preprint]. 2020 Aug 11:2020.08.11.244863. doi: 10.1101/2020.08.11.244863. bioRxiv. 2020. PMID: 32803198 Free PMC article. Updated. Preprint.
374 results