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Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors: identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist.
Burstein ES, Ma J, Wong S, Gao Y, Pham E, Knapp AE, Nash NR, Olsson R, Davis RE, Hacksell U, Weiner DM, Brann MR. Burstein ES, et al. Among authors: pham e. J Pharmacol Exp Ther. 2005 Dec;315(3):1278-87. doi: 10.1124/jpet.105.092155. Epub 2005 Aug 31. J Pharmacol Exp Ther. 2005. PMID: 16135699
Using chimeric mice with humanized livers to predict human drug metabolism and a drug-drug interaction.
Nishimura T, Hu Y, Wu M, Pham E, Suemizu H, Elazar M, Liu M, Idilman R, Yurdaydin C, Angus P, Stedman C, Murphy B, Glenn J, Nakamura M, Nomura T, Chen Y, Zheng M, Fitch WL, Peltz G. Nishimura T, et al. Among authors: pham e. J Pharmacol Exp Ther. 2013 Feb;344(2):388-96. doi: 10.1124/jpet.112.198697. Epub 2012 Nov 8. J Pharmacol Exp Ther. 2013. PMID: 23143674 Free PMC article.
Future Therapy for Hepatitis B Virus: Role of Immunomodulators.
Pham EA, Perumpail RB, Fram BJ, Glenn JS, Ahmed A, Gish RG. Pham EA, et al. Curr Hepatol Rep. 2016;15(4):237-244. doi: 10.1007/s11901-016-0315-9. Epub 2016 Nov 10. Curr Hepatol Rep. 2016. PMID: 27917363 Free PMC article. Review.
Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2.
Hagey RJ, Elazar M, Pham EA, Tian S, Ben-Avi L, Bernardin-Souibgui C, Yee MF, Moreira FR, Rabinovitch MV, Meganck RM, Fram B, Beck A, Gibson SA, Lam G, Devera J, Kladwang W, Nguyen K, Xiong A, Schaffert S, Avisar T, Liu P, Rustagi A, Fichtenbaum CJ, Pang PS, Khatri P, Tseng CT, Taubenberger JK, Blish CA, Hurst BL, Sheahan TP, Das R, Glenn JS. Hagey RJ, et al. Nat Med. 2022 Sep;28(9):1944-1955. doi: 10.1038/s41591-022-01908-x. Epub 2022 Aug 18. Nat Med. 2022. PMID: 35982307 Free PMC article.
163 results