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Hypoxia-regulated microRNAs in human cancer.
Shen G, Li X, Jia YF, Piazza GA, Xi Y. Shen G, et al. Among authors: piazza ga. Acta Pharmacol Sin. 2013 Mar;34(3):336-41. doi: 10.1038/aps.2012.195. Epub 2013 Feb 4. Acta Pharmacol Sin. 2013. PMID: 23377548 Free PMC article. Review.
MicroRNA and cancer chemoprevention.
Yi B, Piazza GA, Su X, Xi Y. Yi B, et al. Among authors: piazza ga. Cancer Prev Res (Phila). 2013 May;6(5):401-9. doi: 10.1158/1940-6207.CAPR-13-0032. Epub 2013 Mar 26. Cancer Prev Res (Phila). 2013. PMID: 23531448 Free PMC article. Review.
An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor κB- and hypoxia-inducible factor 1α-mediated up-regulation of CXCR4.
Arora S, Bhardwaj A, Singh S, Srivastava SK, McClellan S, Nirodi CS, Piazza GA, Grizzle WE, Owen LB, Singh AP. Arora S, et al. Among authors: piazza ga. J Biol Chem. 2013 Jul 19;288(29):21197-21207. doi: 10.1074/jbc.M113.484576. Epub 2013 Jun 5. J Biol Chem. 2013. PMID: 23740244 Free PMC article.
The RAS-Effector Interaction as a Drug Target.
Keeton AB, Salter EA, Piazza GA. Keeton AB, et al. Among authors: piazza ga. Cancer Res. 2017 Jan 15;77(2):221-226. doi: 10.1158/0008-5472.CAN-16-0938. Epub 2017 Jan 6. Cancer Res. 2017. PMID: 28062402 Free PMC article. Review.
Phosphodiesterase 10A is overexpressed in lung tumor cells and inhibitors selectively suppress growth by blocking β-catenin and MAPK signaling.
Zhu B, Lindsey A, Li N, Lee K, Ramirez-Alcantara V, Canzoneri JC, Fajardo A, Madeira da Silva L, Thomas M, Piazza JT, Yet L, Eberhardt BT, Gurpinar E, Otali D, Grizzle W, Valiyaveettil J, Chen X, Keeton AB, Piazza GA. Zhu B, et al. Among authors: piazza jt, piazza ga. Oncotarget. 2017 Aug 27;8(41):69264-69280. doi: 10.18632/oncotarget.20566. eCollection 2017 Sep 19. Oncotarget. 2017. PMID: 29050202 Free PMC article.
Suppression of Colon Tumorigenesis in Mutant Apc Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin.
Lee KJ, Chang WL, Chen X, Valiyaveettil J, Ramirez-Alcantara V, Gavin E, Musiyenko A, Madeira da Silva L, Annamdevula NS, Leavesley SJ, Ward A, Mattox T, Lindsey AS, Andrews J, Zhu B, Wood C, Neese A, Nguyen A, Berry K, Maxuitenko Y, Moyer MP, Nurmemmedov E, Gorman G, Coward L, Zhou G, Keeton AB, Cooper HS, Clapper ML, Piazza GA. Lee KJ, et al. Among authors: piazza ga. Cancer Prev Res (Phila). 2021 Nov;14(11):995-1008. doi: 10.1158/1940-6207.CAPR-21-0208. Epub 2021 Sep 28. Cancer Prev Res (Phila). 2021. PMID: 34584001 Free PMC article.
Phosphodiesterase 10A (PDE10A) as a novel target to suppress β-catenin and RAS signaling in epithelial ovarian cancer.
Borneman RM, Gavin E, Musiyenko A, Richter W, Lee KJ, Crossman DK, Andrews JF, Wilhite AM, McClellan S, Aragon I, Ward AB, Chen X, Keeton AB, Berry K, Piazza GA, Scalici JM, da Silva LM. Borneman RM, et al. Among authors: piazza ga. J Ovarian Res. 2022 Nov 2;15(1):120. doi: 10.1186/s13048-022-01050-9. J Ovarian Res. 2022. PMID: 36324187 Free PMC article.
134 results