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Page 1
New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation.
Fabbri C, Tansey KE, Perlis RH, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D, Breen G, Curtis C, Sang-Hyuk L, Newhouse S, Patel H, Guipponi M, Perroud N, Bondolfi G, O'Donovan M, Lewis G, Biernacka JM, Weinshilboum RM, Farmer A, Aitchison KJ, Craig I, McGuffin P, Uher R, Lewis CM. Fabbri C, et al. Among authors: placentino a. Pharmacogenomics J. 2018 May 22;18(3):413-421. doi: 10.1038/tpj.2017.44. Epub 2017 Nov 21. Pharmacogenomics J. 2018. PMID: 29160301 Free PMC article.
Interaction between serotonin transporter gene variants and life events predicts response to antidepressants in the GENDEP project.
Keers R, Uher R, Huezo-Diaz P, Smith R, Jaffee S, Rietschel M, Henigsberg N, Kozel D, Mors O, Maier W, Zobel A, Hauser J, Souery D, Placentino A, Larsen ER, Dmitrzak-Weglarz M, Gupta B, Hoda F, Craig I, McGuffin P, Farmer AE, Aitchison KJ. Keers R, et al. Among authors: placentino a. Pharmacogenomics J. 2011 Apr;11(2):138-45. doi: 10.1038/tpj.2010.14. Epub 2010 Mar 9. Pharmacogenomics J. 2011. PMID: 20212518
Copy number variants and therapeutic response to antidepressant medication in major depressive disorder.
Tansey KE, Rucker JJ, Kavanagh DH, Guipponi M, Perroud N, Bondolfi G, Domenici E, Evans DM, Hauser J, Henigsberg N, Jerman B, Maier W, Mors O, O'Donovan M, Peters TJ, Placentino A, Rietschel M, Souery D, Aitchison KJ, Craig I, Farmer A, Wendland JR, Malafosse A, Lewis G, Kapur S, McGuffin P, Uher R. Tansey KE, et al. Among authors: placentino a. Pharmacogenomics J. 2014 Aug;14(4):395-9. doi: 10.1038/tpj.2013.51. Epub 2014 Jan 21. Pharmacogenomics J. 2014. PMID: 24445990
Genetic predictors of antidepressant side effects: a grouped candidate gene approach in the Genome-Based Therapeutic Drugs for Depression (GENDEP) study.
Hodgson K, Uher R, Crawford AA, Lewis G, O'Donovan MC, Keers R, Dernovsek MZ, Mors O, Hauser J, Souery D, Maier W, Henigsberg N, Rietschel M, Placentino A, Aitchison K, Farmer A, Davis O, McGuffin P. Hodgson K, et al. Among authors: placentino a. J Psychopharmacol. 2014 Feb;28(2):142-50. doi: 10.1177/0269881113517957. Epub 2014 Jan 10. J Psychopharmacol. 2014. PMID: 24414086
Transcriptomics and the mechanisms of antidepressant efficacy.
Hodgson K, Tansey KE, Powell TR, Coppola G, Uher R, Zvezdana Dernovšek M, Mors O, Hauser J, Souery D, Maier W, Henigsberg N, Rietschel M, Placentino A, Aitchison KJ, Craig IW, Farmer AE, Breen G, McGuffin P, Dobson R. Hodgson K, et al. Among authors: placentino a. Eur Neuropsychopharmacol. 2016 Jan;26(1):105-112. doi: 10.1016/j.euroneuro.2015.10.009. Epub 2015 Nov 12. Eur Neuropsychopharmacol. 2016. PMID: 26621261 Clinical Trial.
Pharmacogenetics of antidepressant response: A polygenic approach.
García-González J, Tansey KE, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D, Žagar T, Czerski PM, Jerman B, Buttenschøn HN, Schulze TG, Zobel A, Farmer A, Aitchison KJ, Craig I, McGuffin P, Giupponi M, Perroud N, Bondolfi G, Evans D, O'Donovan M, Peters TJ, Wendland JR, Lewis G, Kapur S, Perlis R, Arolt V, Domschke K; Major Depressive Disorder Working Group of the Psychiatric Genomic Consortium; Breen G, Curtis C, Sang-Hyuk L, Kan C, Newhouse S, Patel H, Baune BT, Uher R, Lewis CM, Fabbri C. García-González J, et al. Among authors: placentino a. Prog Neuropsychopharmacol Biol Psychiatry. 2017 Apr 3;75:128-134. doi: 10.1016/j.pnpbp.2017.01.011. Epub 2017 Jan 31. Prog Neuropsychopharmacol Biol Psychiatry. 2017. PMID: 28159590 Free article.
Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies.
Fabbri C, Tansey KE, Perlis RH, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D, Breen G, Curtis C, Lee SH, Newhouse S, Patel H, O'Donovan M, Lewis G, Jenkins G, Weinshilboum RM, Farmer A, Aitchison KJ, Craig I, McGuffin P, Schruers K, Biernacka JM, Uher R, Lewis CM. Fabbri C, et al. Among authors: placentino a. Eur Neuropsychopharmacol. 2018 Aug;28(8):945-954. doi: 10.1016/j.euroneuro.2018.05.009. Epub 2018 Jun 28. Eur Neuropsychopharmacol. 2018. PMID: 30135031
Genetic predictors of response to antidepressants in the GENDEP project.
Uher R, Huezo-Diaz P, Perroud N, Smith R, Rietschel M, Mors O, Hauser J, Maier W, Kozel D, Henigsberg N, Barreto M, Placentino A, Dernovsek MZ, Schulze TG, Kalember P, Zobel A, Czerski PM, Larsen ER, Souery D, Giovannini C, Gray JM, Lewis CM, Farmer A, Aitchison KJ, McGuffin P, Craig I. Uher R, et al. Among authors: placentino a. Pharmacogenomics J. 2009 Aug;9(4):225-33. doi: 10.1038/tpj.2009.12. Epub 2009 Apr 14. Pharmacogenomics J. 2009. PMID: 19365399
Moderation of antidepressant response by the serotonin transporter gene.
Huezo-Diaz P, Uher R, Smith R, Rietschel M, Henigsberg N, Marusic A, Mors O, Maier W, Hauser J, Souery D, Placentino A, Zobel A, Larsen ER, Czerski PM, Gupta B, Hoda F, Perroud N, Farmer A, Craig I, Aitchison KJ, McGuffin P. Huezo-Diaz P, et al. Among authors: placentino a. Br J Psychiatry. 2009 Jul;195(1):30-8. doi: 10.1192/bjp.bp.108.062521. Br J Psychiatry. 2009. PMID: 19567893 Clinical Trial.
Genetic predictors of increase in suicidal ideation during antidepressant treatment in the GENDEP project.
Perroud N, Aitchison KJ, Uher R, Smith R, Huezo-Diaz P, Marusic A, Maier W, Mors O, Placentino A, Henigsberg N, Rietschel M, Hauser J, Souery D, Kapelski P, Bonvicini C, Zobel A, Jorgensen L, Petrovic A, Kalember P, Schulze TG, Gupta B, Gray J, Lewis CM, Farmer AE, McGuffin P, Craig I. Perroud N, et al. Among authors: placentino a. Neuropsychopharmacology. 2009 Nov;34(12):2517-28. doi: 10.1038/npp.2009.81. Epub 2009 Jul 29. Neuropsychopharmacology. 2009. PMID: 19641488 Clinical Trial.
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