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The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity.
Crippa V, Cicardi ME, Ramesh N, Seguin SJ, Ganassi M, Bigi I, Diacci C, Zelotti E, Baratashvili M, Gregory JM, Dobson CM, Cereda C, Pandey UB, Poletti A, Carra S. Crippa V, et al. Among authors: poletti a. Hum Mol Genet. 2016 Sep 15;25(18):3908-3924. doi: 10.1093/hmg/ddw232. Epub 2016 Jul 27. Hum Mol Genet. 2016. PMID: 27466192 Free PMC article.
Mutation of SOD1 in ALS: a gain of a loss of function.
Sau D, De Biasi S, Vitellaro-Zuccarello L, Riso P, Guarnieri S, Porrini M, Simeoni S, Crippa V, Onesto E, Palazzolo I, Rusmini P, Bolzoni E, Bendotti C, Poletti A. Sau D, et al. Among authors: poletti a. Hum Mol Genet. 2007 Jul 1;16(13):1604-18. doi: 10.1093/hmg/ddm110. Epub 2007 May 15. Hum Mol Genet. 2007. PMID: 17504823 Free article.
The role of the polyglutamine tract in androgen receptor.
Palazzolo I, Gliozzi A, Rusmini P, Sau D, Crippa V, Simonini F, Onesto E, Bolzoni E, Poletti A. Palazzolo I, et al. Among authors: poletti a. J Steroid Biochem Mol Biol. 2008 Feb;108(3-5):245-53. doi: 10.1016/j.jsbmb.2007.09.016. Epub 2007 Sep 11. J Steroid Biochem Mol Biol. 2008. PMID: 17945479 Review.
The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS).
Crippa V, Sau D, Rusmini P, Boncoraglio A, Onesto E, Bolzoni E, Galbiati M, Fontana E, Marino M, Carra S, Bendotti C, De Biasi S, Poletti A. Crippa V, et al. Among authors: poletti a. Hum Mol Genet. 2010 Sep 1;19(17):3440-56. doi: 10.1093/hmg/ddq257. Epub 2010 Jun 22. Hum Mol Genet. 2010. PMID: 20570967 Free article.
Dysregulation of axonal transport and motorneuron diseases.
Sau D, Rusmini P, Crippa V, Onesto E, Bolzoni E, Ratti A, Poletti A. Sau D, et al. Among authors: poletti a. Biol Cell. 2011 Feb;103(2):87-107. doi: 10.1042/BC20100093. Biol Cell. 2011. PMID: 21250942 Review.
301 results