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FXR-dependent Rubicon induction impairs autophagy in models of human cholestasis.
Panzitt K, Jungwirth E, Krones E, Lee JM, Pollheimer M, Thallinger GG, Kolb-Lenz D, Xiao R, Thorell A, Trauner M, Fickert P, Marschall HU, Moore DD, Wagner M. Panzitt K, et al. Among authors: pollheimer m. J Hepatol. 2020 Jun;72(6):1122-1131. doi: 10.1016/j.jhep.2020.01.014. Epub 2020 Jan 28. J Hepatol. 2020. PMID: 32001325 Free article.
Bile acids trigger cholemic nephropathy in common bile-duct-ligated mice.
Fickert P, Krones E, Pollheimer MJ, Thueringer A, Moustafa T, Silbert D, Halilbasic E, Yang M, Jaeschke H, Stokman G, Wells RG, Eller K, Rosenkranz AR, Eggertsen G, Wagner CA, Langner C, Denk H, Trauner M. Fickert P, et al. Among authors: pollheimer mj. Hepatology. 2013 Dec;58(6):2056-69. doi: 10.1002/hep.26599. Epub 2013 Oct 15. Hepatology. 2013. PMID: 23813550
NorUrsodeoxycholic acid ameliorates cholemic nephropathy in bile duct ligated mice.
Krones E, Eller K, Pollheimer MJ, Racedo S, Kirsch AH, Frauscher B, Wahlström A, Ståhlman M, Trauner M, Grahammer F, Huber TB, Wagner K, Rosenkranz AR, Marschall HU, Fickert P. Krones E, et al. Among authors: pollheimer mj. J Hepatol. 2017 Jul;67(1):110-119. doi: 10.1016/j.jhep.2017.02.019. Epub 2017 Feb 27. J Hepatol. 2017. PMID: 28242240
Differential effects of norUDCA and UDCA in obstructive cholestasis in mice.
Fickert P, Pollheimer MJ, Silbert D, Moustafa T, Halilbasic E, Krones E, Durchschein F, Thüringer A, Zollner G, Denk H, Trauner M. Fickert P, et al. Among authors: pollheimer mj. J Hepatol. 2013 Jun;58(6):1201-8. doi: 10.1016/j.jhep.2013.01.026. Epub 2013 Jan 29. J Hepatol. 2013. PMID: 23369794 Free PMC article.
Characterization of animal models for primary sclerosing cholangitis (PSC).
Fickert P, Pollheimer MJ, Beuers U, Lackner C, Hirschfield G, Housset C, Keitel V, Schramm C, Marschall HU, Karlsen TH, Melum E, Kaser A, Eksteen B, Strazzabosco M, Manns M, Trauner M; International PSC Study Group (IPSCSG). Fickert P, et al. Among authors: pollheimer mj. J Hepatol. 2014 Jun;60(6):1290-303. doi: 10.1016/j.jhep.2014.02.006. Epub 2014 Feb 19. J Hepatol. 2014. PMID: 24560657 Free PMC article. Review.
Cholemic nephropathy - Historical notes and novel perspectives.
Krones E, Pollheimer MJ, Rosenkranz AR, Fickert P. Krones E, et al. Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt B):1356-1366. doi: 10.1016/j.bbadis.2017.08.028. Epub 2017 Aug 26. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 28851656 Free article. Review.
Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis.
Pollheimer MJ, Racedo S, Mikels-Vigdal A, Marshall D, Bowlus C, Lackner C, Madl T, Karlsen TH, Hov JR, Lyman SK, Adamkewicz J, Smith V, Moreau E, Zollner G, Eide TJ, Stojakovic T, Scharnagl H, Gruber HJ, Stauber RE, Trauner M, Fickert P. Pollheimer MJ, et al. J Hepatol. 2018 Aug;69(2):368-377. doi: 10.1016/j.jhep.2018.04.009. Epub 2018 Apr 28. J Hepatol. 2018. PMID: 29709678
Will we ever model PSC? - "it's hard to be a PSC model!".
Pollheimer MJ, Trauner M, Fickert P. Pollheimer MJ, et al. Clin Res Hepatol Gastroenterol. 2011 Dec;35(12):792-804. doi: 10.1016/j.clinre.2011.04.014. Epub 2011 Jun 23. Clin Res Hepatol Gastroenterol. 2011. PMID: 21703962 Review.
69 results