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Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci.
Melum E, Franke A, Schramm C, Weismüller TJ, Gotthardt DN, Offner FA, Juran BD, Laerdahl JK, Labi V, Björnsson E, Weersma RK, Henckaerts L, Teufel A, Rust C, Ellinghaus E, Balschun T, Boberg KM, Ellinghaus D, Bergquist A, Sauer P, Ryu E, Hov JR, Wedemeyer J, Lindkvist B, Wittig M, Porte RJ, Holm K, Gieger C, Wichmann HE, Stokkers P, Ponsioen CY, Runz H, Stiehl A, Wijmenga C, Sterneck M, Vermeire S, Beuers U, Villunger A, Schrumpf E, Lazaridis KN, Manns MP, Schreiber S, Karlsen TH. Melum E, et al. Among authors: porte rj. Nat Genet. 2011 Jan;43(1):17-9. doi: 10.1038/ng.728. Epub 2010 Dec 12. Nat Genet. 2011. PMID: 21151127 Free PMC article.
Three ulcerative colitis susceptibility loci are associated with primary sclerosing cholangitis and indicate a role for IL2, REL, and CARD9.
Janse M, Lamberts LE, Franke L, Raychaudhuri S, Ellinghaus E, Muri Boberg K, Melum E, Folseraas T, Schrumpf E, Bergquist A, Björnsson E, Fu J, Jan Westra H, Groen HJ, Fehrmann RS, Smolonska J, van den Berg LH, Ophoff RA, Porte RJ, Weismüller TJ, Wedemeyer J, Schramm C, Sterneck M, Günther R, Braun F, Vermeire S, Henckaerts L, Wijmenga C, Ponsioen CY, Schreiber S, Karlsen TH, Franke A, Weersma RK. Janse M, et al. Among authors: porte rj. Hepatology. 2011 Jun;53(6):1977-85. doi: 10.1002/hep.24307. Epub 2011 May 2. Hepatology. 2011. PMID: 21425313 Free PMC article.
MMP-2 is a disease-modifying gene in primary sclerosing cholangitis.
Korkmaz KS, de Rooij BJ, van Hoek B, Janse M, Coenraad MJ, van der Reijden JJ, Weersma RK, Porte RJ, Voorneveld PW, Baranski AG, Verspaget HW. Korkmaz KS, et al. Among authors: porte rj. Liver Int. 2014 Feb;34(2):274-80. doi: 10.1111/liv.12237. Epub 2013 Jun 28. Liver Int. 2014. PMID: 23809662
Recipient's genetic R702W NOD2 variant is associated with an increased risk of bacterial infections after orthotopic liver transplantation.
Janse M, de Rooij BJ, van Hoek B, van den Berg AP, Porte RJ, Blokzijl H, Coenraad MJ, Hepkema BG, Schaapherder AF, Ringers J, Weersma RK, Verspaget HW. Janse M, et al. Among authors: porte rj. PLoS One. 2013 Aug 19;8(8):e72617. doi: 10.1371/journal.pone.0072617. eCollection 2013. PLoS One. 2013. PMID: 23977330 Free PMC article.
Donor genetic variants as risk factors for thrombosis after liver transplantation: A genome-wide association study.
Li Y, Nieuwenhuis LM, Voskuil MD, Gacesa R, Hu S, Jansen BH, Venema WTU, Hepkema BG, Blokzijl H, Verkade HJ, Lisman T, Weersma RK, Porte RJ, Festen EAM, de Meijer VE. Li Y, et al. Among authors: porte rj. Am J Transplant. 2021 Sep;21(9):3133-3147. doi: 10.1111/ajt.16490. Epub 2021 Feb 11. Am J Transplant. 2021. PMID: 33445220 Free PMC article.
Current policy for allocation of donor livers in the Netherlands advantages primary sclerosing cholangitis patients on the liver transplantation waiting list-a retrospective study.
Goet JC, Hansen BE, Tieleman M, van Hoek B, van den Berg AP, Polak WG, Dubbeld J, Porte RJ, Konijn-Janssen C, de Man RA, Metselaar HJ, de Vries AC. Goet JC, et al. Among authors: porte rj. Transpl Int. 2018 Jun;31(6):590-599. doi: 10.1111/tri.13097. Epub 2017 Dec 5. Transpl Int. 2018. PMID: 29150966 Free article.
Plasma MMP-2 and MMP-9 and their inhibitors TIMP-1 and TIMP-2 during human orthotopic liver transplantation. The effect of aprotinin and the relation to ischemia/reperfusion injury.
Kuyvenhoven JP, Molenaar IQ, Verspaget HW, Veldman MG, Palareti G, Legnani C, Moolenburgh SE, Terpstra OT, Lamers CB, van Hoek B, Porte RJ. Kuyvenhoven JP, et al. Among authors: porte rj. Thromb Haemost. 2004 Mar;91(3):506-13. doi: 10.1160/TH03-05-0272. Thromb Haemost. 2004. PMID: 14983226 Clinical Trial.
455 results