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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 4
1987 7
1988 11
1989 17
1990 44
1991 67
1992 71
1993 100
1994 105
1995 131
1996 157
1997 134
1998 152
1999 154
2000 175
2001 237
2002 237
2003 236
2004 255
2005 304
2006 268
2007 226
2008 261
2009 190
2010 208
2011 194
2012 180
2013 178
2014 178
2015 150
2016 174
2017 134
2018 125
2019 107
2020 120
2021 106
2022 88
2023 103
2024 39

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5,211 results

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Page 1
Statin therapy increases lipoprotein(a) levels.
Tsimikas S, Gordts PLSM, Nora C, Yeang C, Witztum JL. Tsimikas S, et al. Eur Heart J. 2020 Jun 21;41(24):2275-2284. doi: 10.1093/eurheartj/ehz310. Eur Heart J. 2020. PMID: 31111151
-statin trials, with pre- and on-treatment (4-104 weeks) Lp(a) levels. Statins included atorvastatin 10 mg/day and 80 mg/day, pravastatin 40 mg/day, rosuvastatin 40 mg/day, and pitavastatin 2 mg/day. ...-statin pooled analysis, the ratio of geometric means (95% CI) …
-statin trials, with pre- and on-treatment (4-104 weeks) Lp(a) levels. Statins included atorvastatin 10 mg/day and 80 mg/day, prav …
Aspirin and Pravastatin for Preeclampsia Prevention in High-Risk Pregnancy.
Eid J, Rood KM, Costantine MM. Eid J, et al. Obstet Gynecol Clin North Am. 2023 Mar;50(1):79-88. doi: 10.1016/j.ogc.2022.10.005. Obstet Gynecol Clin North Am. 2023. PMID: 36822711 Review.
In this review, we summarize the evidence behind the use of low-dose aspirin and pravastatin in pregnant individuals at high risk of preeclampsia....
In this review, we summarize the evidence behind the use of low-dose aspirin and pravastatin in pregnant individuals at high risk of …
Pravastatin sodium.
Al-Badr AA, Mostafa GA. Al-Badr AA, et al. Profiles Drug Subst Excip Relat Methodol. 2014;39:433-513. doi: 10.1016/B978-0-12-800173-8.00008-8. Profiles Drug Subst Excip Relat Methodol. 2014. PMID: 24794911 Review.
Pravastatin sodium is an [HMG-CoA] reductase inhibitor and is a lipid-regulating drug. ...The chapter also contains the pharmacokinetics, metabolism, stability, and articles that reviewed pravastatin sodium manufacturing, characterization, and analysis. One hundred …
Pravastatin sodium is an [HMG-CoA] reductase inhibitor and is a lipid-regulating drug. ...The chapter also contains the pharmacokinet …
Pravastatin to treat and prevent preeclampsia. Preclinical and clinical studies.
Girardi G. Girardi G. J Reprod Immunol. 2017 Nov;124:15-20. doi: 10.1016/j.jri.2017.09.009. Epub 2017 Sep 29. J Reprod Immunol. 2017. PMID: 29028516 Review.
In addition, pravastatin is hydrophilic and has a limited passage through the placenta, diminishing any safety concerns. Several pilot studies suggest that pravastatin may be a good option to prevent and treat preeclampsia in women. ...
In addition, pravastatin is hydrophilic and has a limited passage through the placenta, diminishing any safety concerns. Several pilo …
Pravastatin for Preventing and Treating Preeclampsia: A Systematic Review.
Esteve-Valverde E, Ferrer-Oliveras R, Gil-Aliberas N, Baraldès-Farré A, Llurba E, Alijotas-Reig J. Esteve-Valverde E, et al. Obstet Gynecol Surv. 2018 Jan;73(1):40-55. doi: 10.1097/OGX.0000000000000522. Obstet Gynecol Surv. 2018. PMID: 29368790 Review.
IMPORTANCE: We have performed a systematic search to summarize the role of statins for preventing and treating severe preeclampsia. OBJECTIVE: The aim of this study was to examine whether pravastatin is a useful and safe alternative for treating preeclampsia during pregnan …
IMPORTANCE: We have performed a systematic search to summarize the role of statins for preventing and treating severe preeclampsia. OBJECTIV …
In vitro-in vivo extrapolation of transporter-mediated clearance in the liver and kidney.
Kusuhara H, Sugiyama Y. Kusuhara H, et al. Drug Metab Pharmacokinet. 2009;24(1):37-52. doi: 10.2133/dmpk.24.37. Drug Metab Pharmacokinet. 2009. PMID: 19252335 Free article. Review.
This review illustrates the concept of the rate-limiting step in the hepatic elimination mediated by transporters, and describes the prediction of the in vivo pharmacokinetics of drugs whose disposition is determined by transporters, based on in vitro experiments using pravast …
This review illustrates the concept of the rate-limiting step in the hepatic elimination mediated by transporters, and describes the predict …
Statins in Pregnancy: Can We Justify Early Treatment of Reproductive Aged Women?
Pham A, Polic A, Nguyen L, Thompson JL. Pham A, et al. Curr Atheroscler Rep. 2022 Aug;24(8):663-670. doi: 10.1007/s11883-022-01039-1. Epub 2022 Jun 14. Curr Atheroscler Rep. 2022. PMID: 35699821 Review.
However, statin discontinuation is the standard recommendation in pregnant and lactating patients. This review evaluates whether we can justify the early treatment of reproductive aged women with statin therapy. ...Nevertheless, most studies on statins and teratogenicity h …
However, statin discontinuation is the standard recommendation in pregnant and lactating patients. This review evaluates whether we c …
Pravastatin for preeclampsia: From animal to human.
Kumasawa K, Iriyama T, Nagamatsu T, Osuga Y, Fujii T. Kumasawa K, et al. J Obstet Gynaecol Res. 2020 Aug;46(8):1255-1262. doi: 10.1111/jog.14295. Epub 2020 Jun 2. J Obstet Gynaecol Res. 2020. PMID: 32485787
Recently, statins have been reported to improve the regeneration of vascular endothelium, and pravastatin has attracted attention as a potential preventative or therapeutic candidate for preeclampsia. Pravastatin has been demonstrated to have preventative effects in …
Recently, statins have been reported to improve the regeneration of vascular endothelium, and pravastatin has attracted attention as …
Pravastatin: an evidence-based statin?
del Sol AI, Nanayakkara PW. del Sol AI, et al. Expert Opin Drug Metab Toxicol. 2008 Jun;4(6):821-5. doi: 10.1517/17425255.4.6.821. Expert Opin Drug Metab Toxicol. 2008. PMID: 18611121 Review.
With 40 mg pravastatin daily, total cholesterol can be reduced by 25-34% with a very consistent risk reduction of 24% of death from cardiovascular diseases. ...Therefore, when the expected 25-34% LDL cholesterol lowering would be enough to reach an LDL<2.5 mmol/l, treat …
With 40 mg pravastatin daily, total cholesterol can be reduced by 25-34% with a very consistent risk reduction of 24% of death from c …
5,211 results