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Sterol regulatory element-binding protein-1 (SREBP-1) is required to regulate glycogen synthesis and gluconeogenic gene expression in mouse liver.
Ruiz R, Jideonwo V, Ahn M, Surendran S, Tagliabracci VS, Hou Y, Gamble A, Kerner J, Irimia-Dominguez JM, Puchowicz MA, DePaoli-Roach A, Hoppel C, Roach P, Morral N. Ruiz R, et al. Among authors: puchowicz ma. J Biol Chem. 2014 Feb 28;289(9):5510-7. doi: 10.1074/jbc.M113.541110. Epub 2014 Jan 7. J Biol Chem. 2014. PMID: 24398675 Free PMC article.
Mutations in the MPV17 gene are responsible for rapidly progressive liver failure in infancy.
Wong LJ, Brunetti-Pierri N, Zhang Q, Yazigi N, Bove KE, Dahms BB, Puchowicz MA, Gonzalez-Gomez I, Schmitt ES, Truong CK, Hoppel CL, Chou PC, Wang J, Baldwin EE, Adams D, Leslie N, Boles RG, Kerr DS, Craigen WJ. Wong LJ, et al. Among authors: puchowicz ma. Hepatology. 2007 Oct;46(4):1218-27. doi: 10.1002/hep.21799. Hepatology. 2007. PMID: 17694548
A self-defeating anabolic program leads to β-cell apoptosis in endoplasmic reticulum stress-induced diabetes via regulation of amino acid flux.
Krokowski D, Han J, Saikia M, Majumder M, Yuan CL, Guan BJ, Bevilacqua E, Bussolati O, Bröer S, Arvan P, Tchórzewski M, Snider MD, Puchowicz M, Croniger CM, Kimball SR, Pan T, Koromilas AE, Kaufman RJ, Hatzoglou M. Krokowski D, et al. J Biol Chem. 2013 Jun 14;288(24):17202-13. doi: 10.1074/jbc.M113.466920. Epub 2013 May 3. J Biol Chem. 2013. PMID: 23645676 Free PMC article.
Oxidative metabolism: glucose versus ketones.
Prince A, Zhang Y, Croniger C, Puchowicz M. Prince A, et al. Adv Exp Med Biol. 2013;789:323-328. doi: 10.1007/978-1-4614-7411-1_43. Adv Exp Med Biol. 2013. PMID: 23852511
91 results