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Automated high-dimensional flow cytometric data analysis.
Pyne S, Hu X, Wang K, Rossin E, Lin TI, Maier LM, Baecher-Allan C, McLachlan GJ, Tamayo P, Hafler DA, De Jager PL, Mesirov JP. Pyne S, et al. Proc Natl Acad Sci U S A. 2009 May 26;106(21):8519-24. doi: 10.1073/pnas.0903028106. Epub 2009 May 14. Proc Natl Acad Sci U S A. 2009. PMID: 19443687 Free PMC article.
Cytometric profiling in multiple sclerosis uncovers patient population structure and a reduction of CD8low cells.
De Jager PL, Rossin E, Pyne S, Tamayo P, Ottoboni L, Viglietta V, Weiner M, Soler D, Izmailova E, Faron-Yowe L, O'Brien C, Freeman S, Granados S, Parker A, Roubenoff R, Mesirov JP, Khoury SJ, Hafler DA, Weiner HL. De Jager PL, et al. Among authors: pyne s. Brain. 2008 Jul;131(Pt 7):1701-11. doi: 10.1093/brain/awn118. Epub 2008 Jun 21. Brain. 2008. PMID: 18567923 Free PMC article.
A framework for analytical characterization of monoclonal antibodies based on reactivity profiles in different tissues.
Rossin E, Lin TI, Ho HJ, Mentzer SJ, Pyne S. Rossin E, et al. Among authors: pyne s. Bioinformatics. 2011 Oct 1;27(19):2746-53. doi: 10.1093/bioinformatics/btr468. Epub 2011 Aug 16. Bioinformatics. 2011. PMID: 21846734 Free PMC article.
Further, we measured the reactivity of hundreds of new antibodies in diverse tissues using flow cytometry, which we successfully classified using mAbprofiler. First, mAbprofiler fits a mAb's flow cytometric histogram with a finite mixture model of skew t distributions that …
Further, we measured the reactivity of hundreds of new antibodies in diverse tissues using flow cytometry, which we successfully classified …
Critical assessment of automated flow cytometry data analysis techniques.
Aghaeepour N, Finak G; FlowCAP Consortium; DREAM Consortium; Hoos H, Mosmann TR, Brinkman R, Gottardo R, Scheuermann RH. Aghaeepour N, et al. Nat Methods. 2013 Mar;10(3):228-38. doi: 10.1038/nmeth.2365. Epub 2013 Feb 10. Nat Methods. 2013. PMID: 23396282 Free PMC article.
Partial identification in the statistical matching problem.
Ahfock D, Pyne S, Lee SX, McLachlan GJ. Ahfock D, et al. Among authors: pyne s. Comput Stat Data Anal. 2016 Dec;104:79-90. doi: 10.1016/j.csda.2016.06.005. Comput Stat Data Anal. 2016. PMID: 28496285 Free PMC article.
418 results