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Reduced expression of MYC increases longevity and enhances healthspan.
Hofmann JW, Zhao X, De Cecco M, Peterson AL, Pagliaroli L, Manivannan J, Hubbard GB, Ikeno Y, Zhang Y, Feng B, Li X, Serre T, Qi W, Van Remmen H, Miller RA, Bath KG, de Cabo R, Xu H, Neretti N, Sedivy JM. Hofmann JW, et al. Among authors: qi w. Cell. 2015 Jan 29;160(3):477-88. doi: 10.1016/j.cell.2014.12.016. Epub 2015 Jan 22. Cell. 2015. PMID: 25619689 Free PMC article.
Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.
Pérez VI, Cortez LA, Lew CM, Rodriguez M, Webb CR, Van Remmen H, Chaudhuri A, Qi W, Lee S, Bokov A, Fok W, Jones D, Richardson A, Yodoi J, Zhang Y, Tominaga K, Hubbard GB, Ikeno Y. Pérez VI, et al. Among authors: qi w. J Gerontol A Biol Sci Med Sci. 2011 Dec;66(12):1286-99. doi: 10.1093/gerona/glr125. Epub 2011 Aug 26. J Gerontol A Biol Sci Med Sci. 2011. PMID: 21873593 Free PMC article.
Dietary restriction attenuates the accelerated aging phenotype of Sod1(-/-) mice.
Zhang Y, Ikeno Y, Bokov A, Gelfond J, Jaramillo C, Zhang HM, Liu Y, Qi W, Hubbard G, Richardson A, Van Remmen H. Zhang Y, et al. Among authors: qi w. Free Radic Biol Med. 2013 Jul;60:300-6. doi: 10.1016/j.freeradbiomed.2013.02.026. Epub 2013 Feb 28. Free Radic Biol Med. 2013. PMID: 23459073 Free PMC article.
Reduced mitochondrial ROS, enhanced antioxidant defense, and distinct age-related changes in oxidative damage in muscles of long-lived Peromyscus leucopus.
Shi Y, Pulliam DA, Liu Y, Hamilton RT, Jernigan AL, Bhattacharya A, Sloane LB, Qi W, Chaudhuri A, Buffenstein R, Ungvari Z, Austad SN, Van Remmen H. Shi Y, et al. Among authors: qi w. Am J Physiol Regul Integr Comp Physiol. 2013 Mar 1;304(5):R343-55. doi: 10.1152/ajpregu.00139.2012. Epub 2013 Jan 16. Am J Physiol Regul Integr Comp Physiol. 2013. PMID: 23325454 Free PMC article.
Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD.
Jang YC, Liu Y, Hayworth CR, Bhattacharya A, Lustgarten MS, Muller FL, Chaudhuri A, Qi W, Li Y, Huang JY, Verdin E, Richardson A, Van Remmen H. Jang YC, et al. Among authors: qi w. Aging Cell. 2012 Oct;11(5):770-82. doi: 10.1111/j.1474-9726.2012.00843.x. Epub 2012 Aug 2. Aging Cell. 2012. PMID: 22672615 Free PMC article.
3,351 results