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Co-Administration of Adjuvanted Recombinant Ov-103 and Ov-RAL-2 Vaccines Confer Protection against Natural Challenge in A Bovine Onchocerca ochengi Infection Model of Human Onchocerciasis.
Luu L, Bah GS, Okah-Nnane NH, Hartley CS, Glover AF, Walsh TR, Lian LY, Zhan B, Bottazzi ME, Abraham D, Petrovsky N, Bayang N, Tangwa B, Ayiseh RB, Mbah GE, Ekale DD, Tanya VN, Lustigman S, Makepeace BL, Graham-Brown J. Luu L, et al. Vaccines (Basel). 2022 May 27;10(6):861. doi: 10.3390/vaccines10060861. Vaccines (Basel). 2022. PMID: 35746469 Free PMC article.
Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans.
George PJ, Hess JA, Jain S, Patton JB, Zhan T, Tricoche N, Zhan B, Bottazzi ME, Hotez PJ, Abraham D, Lustigman S. George PJ, et al. PLoS Negl Trop Dis. 2019 Sep 16;13(9):e0007730. doi: 10.1371/journal.pntd.0007730. eCollection 2019 Sep. PLoS Negl Trop Dis. 2019. PMID: 31525197 Free PMC article.
Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils.
Zhan B, Arumugam S, Kennedy MW, Tricoche N, Lian LY, Asojo OA, Bennuru S, Bottazzi ME, Hotez PJ, Lustigman S, Klei TR. Zhan B, et al. PLoS Negl Trop Dis. 2018 Oct 8;12(10):e0006772. doi: 10.1371/journal.pntd.0006772. eCollection 2018 Oct. PLoS Negl Trop Dis. 2018. PMID: 30296268 Free PMC article.
Onchocerca volvulus: The Road from Basic Biology to a Vaccine.
Lustigman S, Makepeace BL, Klei TR, Babayan SA, Hotez P, Abraham D, Bottazzi ME. Lustigman S, et al. Trends Parasitol. 2018 Jan;34(1):64-79. doi: 10.1016/j.pt.2017.08.011. Epub 2017 Sep 22. Trends Parasitol. 2018. PMID: 28958602 Free PMC article. Review.
The genome of Onchocerca volvulus, agent of river blindness.
Cotton JA, Bennuru S, Grote A, Harsha B, Tracey A, Beech R, Doyle SR, Dunn M, Hotopp JC, Holroyd N, Kikuchi T, Lambert O, Mhashilkar A, Mutowo P, Nursimulu N, Ribeiro JM, Rogers MB, Stanley E, Swapna LS, Tsai IJ, Unnasch TR, Voronin D, Parkinson J, Nutman TB, Ghedin E, Berriman M, Lustigman S. Cotton JA, et al. Nat Microbiol. 2016 Nov 21;2:16216. doi: 10.1038/nmicrobiol.2016.216. Nat Microbiol. 2016. PMID: 27869790 Free PMC article.
21 results