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The Smac mimetic RMT5265.2HCL induces apoptosis in EBV and HTLV-I associated lymphoma cells by inhibiting XIAP and promoting the mitochondrial release of cytochrome C and Smac.
Leuk Res. 2012 Jun;36(6):784-90. doi: 10.1016/j.leukres.2011.12.024. Epub 2012 Feb 10.
Leuk Res. 2012.
PMID: 22325366
Free PMC article.
Darinaparsin induces a unique cellular response and is active in an arsenic trioxide-resistant myeloma cell line.
Matulis SM, Morales AA, Yehiayan L, Croutch C, Gutman D, Cai Y, Lee KP, Boise LH.
Matulis SM, et al.
Mol Cancer Ther. 2009 May;8(5):1197-206. doi: 10.1158/1535-7163.MCT-08-1072. Epub 2009 May 5.
Mol Cancer Ther. 2009.
PMID: 19417148
Free PMC article.
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