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Year Number of Results
2019 1
2020 3
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2023 3
2024 1

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Page 1
Discovery of an Aldo-Keto reductase 1C3 (AKR1C3) degrader.
Carmona AV, Jonnalagadda S, Case AM, Maddeboina K, Jonnalagadda SK, Dow LF, Duan L, Penning TM, Trippier PC. Carmona AV, et al. Commun Chem. 2024 Apr 29;7(1):95. doi: 10.1038/s42004-024-01177-4. Commun Chem. 2024. PMID: 38684887 Free PMC article.
The evolution of small molecule enzyme activators.
Dow LF, Case AM, Paustian MP, Pinkerton BR, Simeon P, Trippier PC. Dow LF, et al. RSC Med Chem. 2023 Sep 22;14(11):2206-2230. doi: 10.1039/d3md00399j. eCollection 2023 Nov 15. RSC Med Chem. 2023. PMID: 37974956 Review.
Access to Highly Strained Tricyclic Ketals Derived from Coumarins.
Jonnalagadda SK, Huwaimel BI, Jonnalagadda S, Garrison JC, Trippier PC. Jonnalagadda SK, et al. J Org Chem. 2022 Mar 18;87(6):4476-4482. doi: 10.1021/acs.joc.2c00018. Epub 2022 Mar 8. J Org Chem. 2022. PMID: 35258961 Free PMC article.
Aldo-Keto Reductases and Cancer Drug Resistance.
Penning TM, Jonnalagadda S, Trippier PC, Rižner TL. Penning TM, et al. Pharmacol Rev. 2021 Jul;73(3):1150-1171. doi: 10.1124/pharmrev.120.000122. Pharmacol Rev. 2021. PMID: 34312303 Free PMC article. Review.
Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer.
Ashraf-Uz-Zaman M, Shahi S, Akwii R, Sajib MS, Farshbaf MJ, Kallem RR, Putnam W, Wang W, Zhang R, Alvina K, Trippier PC, Mikelis CM, German NA. Ashraf-Uz-Zaman M, et al. Eur J Med Chem. 2021 Jan 1;209:112866. doi: 10.1016/j.ejmech.2020.112866. Epub 2020 Sep 24. Eur J Med Chem. 2021. PMID: 33039722 Free PMC article.
Amide Bond Bioisosteres: Strategies, Synthesis, and Successes.
Kumari S, Carmona AV, Tiwari AK, Trippier PC. Kumari S, et al. J Med Chem. 2020 Nov 12;63(21):12290-12358. doi: 10.1021/acs.jmedchem.0c00530. Epub 2020 Aug 4. J Med Chem. 2020. PMID: 32686940 Free PMC article. Review.
12 results