R01 DK107904/DK/NIDDK NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2016	2
2017	11
2018	10
2019	6
2020	1
2021	5
2022	5
2023	8
2024	1

1

Comprehensive genetic study of the insulin resistance marker TG:HDL-C in the UK Biobank.

Oliveri A, Rebernick RJ, Kuppa A, Pant A, Chen Y, Du X, Cushing KC, Bell HN, Raut C, Prabhu P, Chen VL, Halligan BD, Speliotes EK. Oliveri A, et al. Nat Genet. 2024 Feb;56(2):212-221. doi: 10.1038/s41588-023-01625-2. Epub 2024 Jan 10. Nat Genet. 2024. PMID: 38200128 Free PMC article.

2

LMNA R644C associates with hepatic steatosis in a large cohort and increases cellular lipid droplet accumulation in vitro.

Upadhyay KK, Du X, Chen Y, Speliotes EK, Brady GF. Upadhyay KK, et al. medRxiv [Preprint]. 2023 Dec 22:2023.12.20.23300290. doi: 10.1101/2023.12.20.23300290. medRxiv. 2023. PMID: 38196593 Free PMC article. Preprint.

3

Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease.

Chen Y, Du X, Kuppa A, Feitosa MF, Bielak LF, O'Connell JR, Musani SK, Guo X, Kahali B, Chen VL, Smith AV, Ryan KA, Eirksdottir G, Allison MA, Bowden DW, Budoff MJ, Carr JJ, Chen YI, Taylor KD, Oliveri A, Correa A, Crudup BF, Kardia SLR, Mosley TH Jr, Norris JM, Terry JG, Rotter JI, Wagenknecht LE, Halligan BD, Young KA, Hokanson JE, Washko GR, Gudnason V, Province MA, Peyser PA, Palmer ND, Speliotes EK. Chen Y, et al. Nat Genet. 2023 Oct;55(10):1640-1650. doi: 10.1038/s41588-023-01497-6. Epub 2023 Sep 14. Nat Genet. 2023. PMID: 37709864 Free PMC article.

4

A common variant that alters SUN1 degradation associates with hepatic steatosis and metabolic traits in multiple cohorts.

Upadhyay KK, Du X, Chen Y, Buscher B, Chen VL, Oliveri A, Zhao R, Speliotes EK, Brady GF. Upadhyay KK, et al. J Hepatol. 2023 Nov;79(5):1226-1235. doi: 10.1016/j.jhep.2023.07.036. Epub 2023 Aug 9. J Hepatol. 2023. PMID: 37567366

5

An Assessment of Comparative Medication Durability in Inflammatory Bowel Disease Patients With and Without Co-morbid Psoriasis, Rheumatoid Arthritis, and/or Enteropathic Arthritis.

Cushing K, Gudjonsson JE, Speliotes E, Higgins PDR. Cushing K, et al. Dig Dis Sci. 2023 Oct;68(10):4001-4008. doi: 10.1007/s10620-023-08062-5. Epub 2023 Aug 9. Dig Dis Sci. 2023. PMID: 37555882 Free PMC article.

6

Author Correction: Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology.

Chen VL, Du X, Chen Y, Kuppa A, Handelman SK, Vohnoutka RB, Peyser PA, Palmer ND, Bielak LF, Halligan B, Speliotes EK. Chen VL, et al. Nat Commun. 2023 Jun 8;14(1):3356. doi: 10.1038/s41467-023-38659-3. Nat Commun. 2023. PMID: 37291111 Free PMC article. No abstract available.

7

PNPLA3 Genotype and Diabetes Identify Patients With Nonalcoholic Fatty Liver Disease at High Risk of Incident Cirrhosis.

Chen VL, Oliveri A, Miller MJ, Wijarnpreecha K, Du X, Chen Y, Cushing KC, Lok AS, Speliotes EK. Chen VL, et al. Gastroenterology. 2023 May;164(6):966-977.e17. doi: 10.1053/j.gastro.2023.01.040. Epub 2023 Feb 7. Gastroenterology. 2023. PMID: 36758837

8

Knockout of murine Lyplal1 confers sex-specific protection against diet-induced obesity.

Vohnoutka RB, Kuppa A, Hegde Y, Chen Y, Pant A, Tohme ME, Choi EK, McCarty SM, Bagchi DP, Du X, Chen Y, Chen VL, Mori H, Bielak LF, Maguire LH, Handelman SK, Sexton JZ, Saunders TL, Halligan BD, Speliotes EK. Vohnoutka RB, et al. J Mol Endocrinol. 2023 Mar 10;70(3):e220131. doi: 10.1530/JME-22-0131. Print 2023 Apr 1. J Mol Endocrinol. 2023. PMID: 36748836 Free PMC article.

9

Population-based meta-analysis and gene-set enrichment identifies FXR/RXR pathway as common to fatty liver disease and serum lipids.

Handelman SK, Puentes YM, Kuppa A, Chen Y, Du X, Feitosa MF, Palmer ND, Speliotes EK. Handelman SK, et al. Hepatol Commun. 2022 Nov;6(11):3120-3131. doi: 10.1002/hep4.2066. Epub 2022 Sep 13. Hepatol Commun. 2022. PMID: 36098472 Free PMC article.

10

Polygenic Risk Prediction in Diverticulitis.

De Roo AC, Chen Y, Du X, Handelman S, Byrnes M, Regenbogen SE, Speliotes EK, Maguire LH. De Roo AC, et al. Ann Surg. 2023 Jun 1;277(6):e1262-e1268. doi: 10.1097/SLA.0000000000005623. Epub 2022 Jul 25. Ann Surg. 2023. PMID: 35876359

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