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Collectrin (Tmem27) deficiency in proximal tubules causes hypertension in mice and a TMEM27 variant associates with blood pressure in males in a Latino cohort.
Chu PL, Gigliotti JC, Cechova S, Bodonyi-Kovacs G, Wang YT, Chen L, Wassertheil-Smoller S, Cai J, Isakson BE, Franceschini N, Le TH. Chu PL, et al. Am J Physiol Renal Physiol. 2023 Jan 1;324(1):F30-F42. doi: 10.1152/ajprenal.00176.2022. Epub 2022 Oct 20. Am J Physiol Renal Physiol. 2023. PMID: 36264884 Free PMC article.
Urine Uromodulin and Genetics of its Variation.
Franceschini N, Le TH. Franceschini N, et al. J Am Soc Nephrol. 2022 Mar;33(3):461-462. doi: 10.1681/ASN.2022010027. J Am Soc Nephrol. 2022. PMID: 35228296 Free PMC article. No abstract available.
Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.
Morris AP, Le TH, Wu H, Akbarov A, van der Most PJ, Hemani G, Smith GD, Mahajan A, Gaulton KJ, Nadkarni GN, Valladares-Salgado A, Wacher-Rodarte N, Mychaleckyj JC, Dueker ND, Guo X, Hai Y, Haessler J, Kamatani Y, Stilp AM, Zhu G, Cook JP, Ärnlöv J, Blanton SH, de Borst MH, Bottinger EP, Buchanan TA, Cechova S, Charchar FJ, Chu PL, Damman J, Eales J, Gharavi AG, Giedraitis V, Heath AC, Ipp E, Kiryluk K, Kramer HJ, Kubo M, Larsson A, Lindgren CM, Lu Y, Madden PAF, Montgomery GW, Papanicolaou GJ, Raffel LJ, Sacco RL, Sanchez E, Stark H, Sundstrom J, Taylor KD, Xiang AH, Zivkovic A, Lind L, Ingelsson E, Martin NG, Whitfield JB, Cai J, Laurie CC, Okada Y, Matsuda K, Kooperberg C, Chen YI, Rundek T, Rich SS, Loos RJF, Parra EJ, Cruz M, Rotter JI, Snieder H, Tomaszewski M, Humphreys BD, Franceschini N. Morris AP, et al. Nat Commun. 2019 Jan 3;10(1):29. doi: 10.1038/s41467-018-07867-7. Nat Commun. 2019. PMID: 30604766 Free PMC article.
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