R01 HL115140/HL/NHLBI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2013	1
2014	4
2015	1
2016	3
2017	3
2018	4
2019	4
2023	1
2024	0

1

Long-Term Treatment with Gadopentetic Acid or Gadodiamide Increases TRPC5 Expression and Decreases Adriamycin Nuclear Accumulation in Breast Cancer Cells.

Zhang W, Wang M, Lv W, White FA, Chen X, Obukhov AG. Zhang W, et al. Cells. 2023 May 3;12(9):1304. doi: 10.3390/cells12091304. Cells. 2023. PMID: 37174704 Free PMC article.

2

Bone Marrow-Derived Cells Restore Functional Integrity of the Gut Epithelial and Vascular Barriers in a Model of Diabetes and ACE2 Deficiency.

Duan Y, Prasad R, Feng D, Beli E, Li Calzi S, Longhini ALF, Lamendella R, Floyd JL, Dupont M, Noothi SK, Sreejit G, Athmanathan B, Wright J, Jensen AR, Oudit GY, Markel TA, Nagareddy PR, Obukhov AG, Grant MB. Duan Y, et al. Circ Res. 2019 Nov 8;125(11):969-988. doi: 10.1161/CIRCRESAHA.119.315743. Epub 2019 Oct 15. Circ Res. 2019. PMID: 31610731 Free PMC article.

3

Long-Term Diabetic Microenvironment Augments the Decay Rate of Capsaicin-Induced Currents in Mouse Dorsal Root Ganglion Neurons.

Chen X, Duan Y, Riley AM, Welch MA, White FA, Grant MB, Obukhov AG. Chen X, et al. Molecules. 2019 Feb 21;24(4):775. doi: 10.3390/molecules24040775. Molecules. 2019. PMID: 30795543 Free PMC article.

4

The TRPC6 inhibitor, larixyl acetate, is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction.

Chen X, Taylor-Nguyen NN, Riley AM, Herring BP, White FA, Obukhov AG. Chen X, et al. J Neuroinflammation. 2019 Jan 31;16(1):21. doi: 10.1186/s12974-019-1407-6. J Neuroinflammation. 2019. PMID: 30704505 Free PMC article.

5

R125H, W240S, C386R, and V507I SLC4A11 mutations associated with corneal endothelial dystrophy affect the transporter function but not trafficking in PS120 cells.

Li S, Hundal KS, Chen X, Choi M, Ogando DG, Obukhov AG, Bonanno JA. Li S, et al. Exp Eye Res. 2019 Mar;180:86-91. doi: 10.1016/j.exer.2018.12.003. Epub 2018 Dec 14. Exp Eye Res. 2019. PMID: 30557570 Free PMC article.

6

Small-molecule Ca_Vα₁⋅Ca_Vβ antagonist suppresses neuronal voltage-gated calcium-channel trafficking.

Chen X, Liu D, Zhou D, Si Y, Xu D, Stamatkin CW, Ghozayel MK, Ripsch MS, Obukhov AG, White FA, Meroueh SO. Chen X, et al. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10566-E10575. doi: 10.1073/pnas.1813157115. Epub 2018 Oct 24. Proc Natl Acad Sci U S A. 2018. PMID: 30355767 Free PMC article.

7

Phenylephrine, a common cold remedy active ingredient, suppresses uterine contractions through cAMP signalling.

Chen X, Meroueh M, Mazur G, Rouse E, Hundal KS, Stamatkin CW, Obukhov AG. Chen X, et al. Sci Rep. 2018 Aug 3;8(1):11666. doi: 10.1038/s41598-018-30094-5. Sci Rep. 2018. PMID: 30076382 Free PMC article.

8

Loss of Angiotensin-Converting Enzyme 2 Exacerbates Diabetic Retinopathy by Promoting Bone Marrow Dysfunction.

Duan Y, Beli E, Li Calzi S, Quigley JL, Miller RC, Moldovan L, Feng D, Salazar TE, Hazra S, Al-Sabah J, Chalam KV, Phuong Trinh TL, Meroueh M, Markel TA, Murray MC, Vyas RJ, Boulton ME, Parsons-Wingerter P, Oudit GY, Obukhov AG, Grant MB. Duan Y, et al. Stem Cells. 2018 Sep;36(9):1430-1440. doi: 10.1002/stem.2848. Epub 2018 Jul 15. Stem Cells. 2018. PMID: 29761600 Free PMC article.

9

Long-term spironolactone treatment reduces coronary TRPC expression, vasoconstriction, and atherosclerosis in metabolic syndrome pigs.

Li W, Chen X, Riley AM, Hiett SC, Temm CJ, Beli E, Long X, Chakraborty S, Alloosh M, White FA, Grant MB, Sturek M, Obukhov AG. Li W, et al. Basic Res Cardiol. 2017 Sep;112(5):54. doi: 10.1007/s00395-017-0643-0. Epub 2017 Jul 29. Basic Res Cardiol. 2017. PMID: 28756533 Free PMC article.

10

Molecular Determinants of the Sensitivity to Gq/11-Phospholipase C-dependent Gating, Gd3+ Potentiation, and Ca2+ Permeability in the Transient Receptor Potential Canonical Type 5 (TRPC5) Channel.

Chen X, Li W, Riley AM, Soliman M, Chakraborty S, Stamatkin CW, Obukhov AG. Chen X, et al. J Biol Chem. 2017 Jan 20;292(3):898-911. doi: 10.1074/jbc.M116.755470. Epub 2016 Dec 5. J Biol Chem. 2017. PMID: 27920205 Free PMC article.

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