R01 HL134780/HL/NHLBI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2018	7
2019	9
2020	7
2021	7
2022	7
2024	0

1

Aberrant DNA hydroxymethylation reshapes transcription factor binding in myeloid neoplasms.

Li J, Hong T, Wei Y, Guo L, Lee M, Yang H, Class C, Yang Y, Wang X, He H, Siwko S, You MJ, Zhou Y, Garcia-Manero G, Huang Y. Li J, et al. Clin Epigenetics. 2022 Jun 28;14(1):81. doi: 10.1186/s13148-022-01297-5. Clin Epigenetics. 2022. PMID: 35765052 Free PMC article.

2

Optogenetics for transcriptional programming and genetic engineering.

Lan TH, He L, Huang Y, Zhou Y. Lan TH, et al. Trends Genet. 2022 Dec;38(12):1253-1270. doi: 10.1016/j.tig.2022.05.014. Epub 2022 Jun 20. Trends Genet. 2022. PMID: 35738948 Free PMC article. Review.

3

The disordered N-terminal domain of DNMT3A recognizes H2AK119ub and is required for postnatal development.

Gu T, Hao D, Woo J, Huang TW, Guo L, Lin X, Guzman AG, Tovy A, Rosas C, Jeong M, Zhou Y, Deneen B, Huang Y, Li W, Goodell MA. Gu T, et al. Nat Genet. 2022 May;54(5):625-636. doi: 10.1038/s41588-022-01063-6. Epub 2022 May 9. Nat Genet. 2022. PMID: 35534561 Free PMC article.

4

Red-shifted optogenetics comes to the spotlight.

Wang T, Liu S, Huang Y, Zhou Y. Wang T, et al. Clin Transl Med. 2022 Apr;12(4):e807. doi: 10.1002/ctm2.807. Clin Transl Med. 2022. PMID: 35389568 Free PMC article. No abstract available.

5

Optophysiology: Illuminating cell physiology with optogenetics.

Tan P, He L, Huang Y, Zhou Y. Tan P, et al. Physiol Rev. 2022 Jul 1;102(3):1263-1325. doi: 10.1152/physrev.00021.2021. Epub 2022 Jan 24. Physiol Rev. 2022. PMID: 35072525 Free PMC article. Review.

6

Altered Chromatin States Drive Cryptic Transcription in Aging Mammalian Stem Cells.

McCauley BS, Sun L, Yu R, Lee M, Liu H, Leeman DS, Huang Y, Webb AE, Dang W. McCauley BS, et al. Nat Aging. 2021 Aug;1(8):684-697. doi: 10.1038/s43587-021-00091-x. Epub 2021 Aug 2. Nat Aging. 2021. PMID: 34746802 Free PMC article.

7

Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor.

Huang YH, Chen CW, Sundaramurthy V, Słabicki M, Hao D, Watson CJ, Tovy A, Reyes JM, Dakhova O, Crovetti BR, Galonska C, Lee M, Brunetti L, Zhou Y, Tatton-Brown K, Huang Y, Cheng X, Meissner A, Valk PJM, Van Maldergem L, Sanders MA, Blundell JR, Li W, Ebert BL, Goodell MA. Huang YH, et al. Cancer Discov. 2022 Jan;12(1):220-235. doi: 10.1158/2159-8290.CD-21-0560. Epub 2021 Aug 24. Cancer Discov. 2022. PMID: 34429321 Free PMC article.

8

Design of Smart Antibody Mimetics with Photosensitive Switches.

He L, Tan P, Huang Y, Zhou Y. He L, et al. Adv Biol (Weinh). 2021 May;5(5):e2000541. doi: 10.1002/adbi.202000541. Epub 2021 Feb 5. Adv Biol (Weinh). 2021. PMID: 34028213 Free PMC article.

9

Preferential CEBP binding to T:G mismatches and increased C-to-T human somatic mutations.

Yang J, Horton JR, Akdemir KC, Li J, Huang Y, Kumar J, Blumenthal RM, Zhang X, Cheng X. Yang J, et al. Nucleic Acids Res. 2021 May 21;49(9):5084-5094. doi: 10.1093/nar/gkab276. Nucleic Acids Res. 2021. PMID: 33877329 Free PMC article.

10

Tet2 Inactivation Enhances the Antitumor Activity of Tumor-Infiltrating Lymphocytes.

Lee M, Li J, Li J, Fang S, Zhang J, Vo ATT, Han W, Zeng H, Isgandarova S, Martinez-Moczygemba M, Zhou Y, Sun D, Huang Y. Lee M, et al. Cancer Res. 2021 Apr 15;81(8):1965-1976. doi: 10.1158/0008-5472.CAN-20-3213. Epub 2021 Feb 15. Cancer Res. 2021. PMID: 33589517 Free PMC article.

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