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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2010 | 1 |
2011 | 2 |
2012 | 1 |
2013 | 1 |
2014 | 2 |
2021 | 1 |
2024 | 0 |
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7 results
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Page 1
Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2.
Bioorg Med Chem. 2021 Sep 15;46:116349. doi: 10.1016/j.bmc.2021.116349. Epub 2021 Aug 5.
Bioorg Med Chem. 2021.
PMID: 34500187
Free PMC article.
Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapies.
Rai G, Joshi N, Jung JE, Liu Y, Schultz L, Yasgar A, Perry S, Diaz G, Zhang Q, Kenyon V, Jadhav A, Simeonov A, Lo EH, van Leyen K, Maloney DJ, Holman TR.
Rai G, et al.
J Med Chem. 2014 May 22;57(10):4035-48. doi: 10.1021/jm401915r. Epub 2014 May 13.
J Med Chem. 2014.
PMID: 24684213
Free PMC article.
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Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase.
Luci DK, Jameson JB 2nd, Yasgar A, Diaz G, Joshi N, Kantz A, Markham K, Perry S, Kuhn N, Yeung J, Kerns EH, Schultz L, Holinstat M, Nadler JL, Taylor-Fishwick DA, Jadhav A, Simeonov A, Holman TR, Maloney DJ.
Luci DK, et al.
J Med Chem. 2014 Jan 23;57(2):495-506. doi: 10.1021/jm4016476. Epub 2014 Jan 6.
J Med Chem. 2014.
PMID: 24393039
Free PMC article.
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12-lipoxygenase activity plays an important role in PAR4 and GPVI-mediated platelet reactivity.
Yeung J, Apopa PL, Vesci J, Stolla M, Rai G, Simeonov A, Jadhav A, Fernandez-Perez P, Maloney DJ, Boutaud O, Holman TR, Holinstat M.
Yeung J, et al.
Thromb Haemost. 2013 Sep;110(3):569-81. doi: 10.1160/TH13-01-0014. Epub 2013 Jun 20.
Thromb Haemost. 2013.
PMID: 23784669
Free PMC article.
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Protein kinase C regulation of 12-lipoxygenase-mediated human platelet activation.
Yeung J, Apopa PL, Vesci J, Kenyon V, Rai G, Jadhav A, Simeonov A, Holman TR, Maloney DJ, Boutaud O, Holinstat M.
Yeung J, et al.
Mol Pharmacol. 2012 Mar;81(3):420-30. doi: 10.1124/mol.111.075630. Epub 2011 Dec 9.
Mol Pharmacol. 2012.
PMID: 22155783
Free PMC article.
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Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.
Kenyon V, Rai G, Jadhav A, Schultz L, Armstrong M, Jameson JB 2nd, Perry S, Joshi N, Bougie JM, Leister W, Taylor-Fishwick DA, Nadler JL, Holinstat M, Simeonov A, Maloney DJ, Holman TR.
Kenyon V, et al.
J Med Chem. 2011 Aug 11;54(15):5485-97. doi: 10.1021/jm2005089. Epub 2011 Jul 8.
J Med Chem. 2011.
PMID: 21739938
Free PMC article.
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Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.
Rai G, Kenyon V, Jadhav A, Schultz L, Armstrong M, Jameson JB, Hoobler E, Leister W, Simeonov A, Holman TR, Maloney DJ.
Rai G, et al.
J Med Chem. 2010 Oct 28;53(20):7392-404. doi: 10.1021/jm1008852.
J Med Chem. 2010.
PMID: 20866075
Free PMC article.
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