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Biomarkers in the ICU: less is more? Yes.
Huang DT, Ramirez P. Huang DT, et al. Intensive Care Med. 2021 Jan;47(1):94-96. doi: 10.1007/s00134-020-06049-8. Epub 2020 Apr 28. Intensive Care Med. 2021. PMID: 32347324 Free PMC article. No abstract available.
Longer-Term Outcomes of the ProACT Trial.
Huang DT, Yealy DM, Angus DC; ProACT Investigators. Huang DT, et al. N Engl J Med. 2020 Jan 30;382(5):485-486. doi: 10.1056/NEJMc1910508. N Engl J Med. 2020. PMID: 31995699 Free PMC article. No abstract available.
Procalcitonin: Where Are We Now?
Hamade B, Huang DT. Hamade B, et al. Crit Care Clin. 2020 Jan;36(1):23-40. doi: 10.1016/j.ccc.2019.08.003. Epub 2019 Oct 21. Crit Care Clin. 2020. PMID: 31733680 Free PMC article. Review.
Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis.
Seymour CW, Kennedy JN, Wang S, Chang CH, Elliott CF, Xu Z, Berry S, Clermont G, Cooper G, Gomez H, Huang DT, Kellum JA, Mi Q, Opal SM, Talisa V, van der Poll T, Visweswaran S, Vodovotz Y, Weiss JC, Yealy DM, Yende S, Angus DC. Seymour CW, et al. JAMA. 2019 May 28;321(20):2003-2017. doi: 10.1001/jama.2019.5791. JAMA. 2019. PMID: 31104070 Free PMC article.
Procalcitonin-Guided Use of Antibiotics for Lower Respiratory Tract Infection.
Huang DT, Yealy DM, Filbin MR, Brown AM, Chang CH, Doi Y, Donnino MW, Fine J, Fine MJ, Fischer MA, Holst JM, Hou PC, Kellum JA, Khan F, Kurz MC, Lotfipour S, LoVecchio F, Peck-Palmer OM, Pike F, Prunty H, Sherwin RL, Southerland L, Terndrup T, Weissfeld LA, Yabes J, Angus DC; ProACT Investigators. Huang DT, et al. N Engl J Med. 2018 Jul 19;379(3):236-249. doi: 10.1056/NEJMoa1802670. Epub 2018 May 20. N Engl J Med. 2018. PMID: 29781385 Free PMC article. Clinical Trial.
Design and rationale of the Procalcitonin Antibiotic Consensus Trial (ProACT), a multicenter randomized trial of procalcitonin antibiotic guidance in lower respiratory tract infection.
Huang DT, Angus DC, Chang CH, Doi Y, Fine MJ, Kellum JA, Peck-Palmer OM, Pike F, Weissfeld LA, Yabes J, Yealy DM; ProACT Investigators. Huang DT, et al. BMC Emerg Med. 2017 Aug 29;17(1):25. doi: 10.1186/s12873-017-0138-1. BMC Emerg Med. 2017. PMID: 28851296 Free PMC article. Clinical Trial.