R35 GM134744/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2020	6
2021	11
2022	11
2023	9
2024	0

1

Structures of CTCF-DNA complexes including all 11 zinc fingers.

Yang J, Horton JR, Liu B, Corces VG, Blumenthal RM, Zhang X, Cheng X. Yang J, et al. Nucleic Acids Res. 2023 Sep 8;51(16):8447-8462. doi: 10.1093/nar/gkad594. Nucleic Acids Res. 2023. PMID: 37439339 Free PMC article.

2

Biochemical and structural characterization of the first-discovered metazoan DNA cytosine-N4 methyltransferase from the bdelloid rotifer Adineta vaga.

Zhou J, Horton JR, Kaur G, Chen Q, Li X, Mendoza F, Wu T, Blumenthal RM, Zhang X, Cheng X. Zhou J, et al. J Biol Chem. 2023 Aug;299(8):105017. doi: 10.1016/j.jbc.2023.105017. Epub 2023 Jul 5. J Biol Chem. 2023. PMID: 37414145 Free PMC article.

3

GSK-3484862 targets DNMT1 for degradation in cells.

Chen Q, Liu B, Zeng Y, Hwang JW, Dai N, Corrêa IR Jr, Estecio MR, Zhang X, Santos MA, Chen T, Cheng X. Chen Q, et al. NAR Cancer. 2023 May 17;5(2):zcad022. doi: 10.1093/narcan/zcad022. eCollection 2023 Jun. NAR Cancer. 2023. PMID: 37206360 Free PMC article.

4

Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile-Specific DNA Adenine Methyltransferase.

Zhou J, Deng Y, Iyamu ID, Horton JR, Yu D, Hajian T, Vedadi M, Rotili D, Mai A, Blumenthal RM, Zhang X, Huang R, Cheng X. Zhou J, et al. ACS Chem Biol. 2023 Apr 21;18(4):734-745. doi: 10.1021/acschembio.3c00035. Epub 2023 Feb 22. ACS Chem Biol. 2023. PMID: 37082867 Free PMC article.

5

Allosteric autoregulation of DNA binding via a DNA-mimicking protein domain: a biophysical study of ZNF410-DNA interaction using small angle X-ray scattering.

Kaur G, Ren R, Hammel M, Horton JR, Yang J, Cao Y, He C, Lan F, Lan X, Blobel GA, Blumenthal RM, Zhang X, Cheng X. Kaur G, et al. Nucleic Acids Res. 2023 Feb 28;51(4):1674-1686. doi: 10.1093/nar/gkac1274. Nucleic Acids Res. 2023. PMID: 36660822 Free PMC article.

6

Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.

Ren R, Horton JR, Chen Q, Yang J, Liu B, Huang Y, Blumenthal RM, Zhang X, Cheng X. Ren R, et al. J Biol Chem. 2023 Feb;299(2):102885. doi: 10.1016/j.jbc.2023.102885. Epub 2023 Jan 7. J Biol Chem. 2023. PMID: 36626981 Free PMC article.

7

A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2.

Horton JR, Zhou J, Chen Q, Zhang X, Bedford MT, Cheng X. Horton JR, et al. J Biol Chem. 2023 Feb;299(2):102862. doi: 10.1016/j.jbc.2022.102862. Epub 2022 Dec 31. J Biol Chem. 2023. PMID: 36596360 Free PMC article.

8

Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence.

Zhou J, Horton JR, Menna M, Fiorentino F, Ren R, Yu D, Hajian T, Vedadi M, Mazzoccanti G, Ciogli A, Weinhold E, Hüben M, Blumenthal RM, Zhang X, Mai A, Rotili D, Cheng X. Zhou J, et al. J Med Chem. 2023 Jan 12;66(1):934-950. doi: 10.1021/acs.jmedchem.2c01789. Epub 2022 Dec 29. J Med Chem. 2023. PMID: 36581322 Free PMC article.

9

Expansion of the genotypic and phenotypic spectrum of CTCF-related disorder guides clinical management: 43 new subjects and a comprehensive literature review.

Valverde de Morales HG, Wang HV, Garber K, Cheng X, Corces VG, Li H. Valverde de Morales HG, et al. Am J Med Genet A. 2023 Mar;191(3):718-729. doi: 10.1002/ajmg.a.63065. Epub 2022 Dec 1. Am J Med Genet A. 2023. PMID: 36454652 Free PMC article. Review.

10

Recent Advances on DNA Base Flipping: A General Mechanism for Writing, Reading, and Erasing DNA Modifications.

Ren R, Horton JR, Hong S, Cheng X. Ren R, et al. Adv Exp Med Biol. 2022;1389:295-315. doi: 10.1007/978-3-031-11454-0_12. Adv Exp Med Biol. 2022. PMID: 36350515 Free PMC article.

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