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8-Substituted 1,3-dimethyltetrahydropyrazino[2,1-f]purinediones: Water-soluble adenosine receptor antagonists and monoamine oxidase B inhibitors.
Bioorg Med Chem. 2016 Nov 1;24(21):5462-5480. doi: 10.1016/j.bmc.2016.09.003. Epub 2016 Sep 3.
Bioorg Med Chem. 2016.
PMID: 27658798
1,3-Dialkyl-substituted tetrahydropyrimido[1,2-f]purine-2,4-diones as multiple target drugs for the potential treatment of neurodegenerative diseases.
Koch P, Akkari R, Brunschweiger A, Borrmann T, Schlenk M, Küppers P, Köse M, Radjainia H, Hockemeyer J, Drabczyńska A, Kieć-Kononowicz K, Müller CE.
Koch P, et al. Among authors: radjainia h.
Bioorg Med Chem. 2013 Dec 1;21(23):7435-52. doi: 10.1016/j.bmc.2013.09.044. Epub 2013 Sep 25.
Bioorg Med Chem. 2013.
PMID: 24139167
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Adenosine A(2A) receptor blockade reverts hippocampal stress-induced deficits and restores corticosterone circadian oscillation.
Batalha VL, Pego JM, Fontinha BM, Costenla AR, Valadas JS, Baqi Y, Radjainia H, Müller CE, Sebastião AM, Lopes LV.
Batalha VL, et al. Among authors: radjainia h.
Mol Psychiatry. 2013 Mar;18(3):320-31. doi: 10.1038/mp.2012.8. Epub 2012 Feb 28.
Mol Psychiatry. 2013.
PMID: 22371048
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