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Fragile X protein mitigates TDP-43 toxicity by remodeling RNA granules and restoring translation.
Coyne AN, Yamada SB, Siddegowda BB, Estes PS, Zaepfel BL, Johannesmeyer JS, Lockwood DB, Pham LT, Hart MP, Cassel JA, Freibaum B, Boehringer AV, Taylor JP, Reitz AB, Gitler AD, Zarnescu DC. Coyne AN, et al. Among authors: reitz ab. Hum Mol Genet. 2015 Dec 15;24(24):6886-98. doi: 10.1093/hmg/ddv389. Epub 2015 Sep 18. Hum Mol Genet. 2015. PMID: 26385636 Free PMC article.
Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.
Messick TE, Smith GR, Soldan SS, McDonnell ME, Deakyne JS, Malecka KA, Tolvinski L, van den Heuvel APJ, Gu BW, Cassel JA, Tran DH, Wassermann BR, Zhang Y, Velvadapu V, Zartler ER, Busson P, Reitz AB, Lieberman PM. Messick TE, et al. Among authors: reitz ab. Sci Transl Med. 2019 Mar 6;11(482):eaau5612. doi: 10.1126/scitranslmed.aau5612. Sci Transl Med. 2019. PMID: 30842315 Free PMC article.
N-aryl-N'-benzylpiperazines as potential antipsychotic agents.
Reitz AB, Baxter EW, Bennett DJ, Codd EE, Jordan AD, Malloy EA, Maryanoff BE, McDonnell ME, Ortegon ME, Renzi MJ, et al. Reitz AB, et al. J Med Chem. 1995 Oct 13;38(21):4211-22. doi: 10.1021/jm00021a010. J Med Chem. 1995. PMID: 7473548
alpha(2) Adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-Imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene [corrected] as a high-affinity ligand for the alpha(2D) adrenergic receptor.
Ross TM, Jetter MC, McDonnell ME, Boyd RE, Connelly CD, Martinez RP, Lewis MA, Codd EE, Raffa RB, Reitz AB. Ross TM, et al. Among authors: reitz ab. J Med Chem. 2000 Mar 9;43(5):765-8. doi: 10.1021/jm990569e. J Med Chem. 2000. PMID: 10715142 Corrected and republished. No abstract available.
143 results