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Page 1
Prostate apoptosis response-4 is expressed in normal cholangiocytes, is down-regulated in human cholangiocarcinoma, and promotes apoptosis of neoplastic cholangiocytes when induced pharmacologically.
Franchitto A, Torrice A, Semeraro R, Napoli C, Nuzzo G, Giuliante F, Alpini G, Carpino G, Berloco PB, Izzo L, Bolognese A, Onori P, Renzi A, Cantafora A, Gaudio E, Alvaro D. Franchitto A, et al. Among authors: renzi a. Am J Pathol. 2010 Oct;177(4):1779-90. doi: 10.2353/ajpath.2010.091171. Epub 2010 Aug 19. Am J Pathol. 2010. PMID: 20724592 Free PMC article.
Knockout of the neurokinin-1 receptor reduces cholangiocyte proliferation in bile duct-ligated mice.
Glaser S, Gaudio E, Renzi A, Mancinelli R, Ueno Y, Venter J, White M, Kopriva S, Chiasson V, DeMorrow S, Francis H, Meng F, Marzioni M, Franchitto A, Alvaro D, Supowit S, DiPette DJ, Onori P, Alpini G. Glaser S, et al. Among authors: renzi a. Am J Physiol Gastrointest Liver Physiol. 2011 Aug;301(2):G297-305. doi: 10.1152/ajpgi.00418.2010. Epub 2011 May 19. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21596993 Free PMC article.
Melatonin inhibits cholangiocyte hyperplasia in cholestatic rats by interaction with MT1 but not MT2 melatonin receptors.
Renzi A, Glaser S, Demorrow S, Mancinelli R, Meng F, Franchitto A, Venter J, White M, Francis H, Han Y, Alvaro D, Gaudio E, Carpino G, Ueno Y, Onori P, Alpini G. Renzi A, et al. Am J Physiol Gastrointest Liver Physiol. 2011 Oct;301(4):G634-43. doi: 10.1152/ajpgi.00206.2011. Epub 2011 Jul 14. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21757639 Free PMC article.
Melatonin exerts by an autocrine loop antiproliferative effects in cholangiocarcinoma: its synthesis is reduced favoring cholangiocarcinoma growth.
Han Y, Demorrow S, Invernizzi P, Jing Q, Glaser S, Renzi A, Meng F, Venter J, Bernuzzi F, White M, Francis H, Lleo A, Marzioni M, Onori P, Alvaro D, Torzilli G, Gaudio E, Alpini G. Han Y, et al. Among authors: renzi a. Am J Physiol Gastrointest Liver Physiol. 2011 Oct;301(4):G623-33. doi: 10.1152/ajpgi.00118.2011. Epub 2011 Jul 21. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21778461 Free PMC article.
Histamine stimulates the proliferation of small and large cholangiocytes by activation of both IP3/Ca2+ and cAMP-dependent signaling mechanisms.
Francis HL, Demorrow S, Franchitto A, Venter JK, Mancinelli RA, White MA, Meng F, Ueno Y, Carpino G, Renzi A, Baker KK, Shine HE, Francis TC, Gaudio E, Alpini GD, Onori P. Francis HL, et al. Among authors: renzi a. Lab Invest. 2012 Feb;92(2):282-94. doi: 10.1038/labinvest.2011.158. Epub 2011 Nov 7. Lab Invest. 2012. PMID: 22064319 Free PMC article.
Modulation of the biliary expression of arylalkylamine N-acetyltransferase alters the autocrine proliferative responses of cholangiocytes in rats.
Renzi A, DeMorrow S, Onori P, Carpino G, Mancinelli R, Meng F, Venter J, White M, Franchitto A, Francis H, Han Y, Ueno Y, Dusio G, Jensen KJ, Greene JJ Jr, Glaser S, Gaudio E, Alpini G. Renzi A, et al. Hepatology. 2013 Mar;57(3):1130-41. doi: 10.1002/hep.26105. Epub 2013 Feb 7. Hepatology. 2013. PMID: 23080076 Free PMC article.
309 results